顶下叶在汉语声调感知中的作用：fNIRS导航的TMS研究

doi:10.3724/SP.J.1041.2026.1343

摘要/Abstract

摘要： 左侧顶下叶(IPL)是语音范畴感知的重要脑区, 它同样参与了汉语声调感知, 但是对其功能认识还没有得到一致的结论。本研究使用功能性近红外光谱(fNIRS)技术对左侧IPL参与声调感知进行功能定位(实验1), 然后使用经颅磁刺激(TMS)技术对左侧IPL进行虚拟损伤(实验2), 建立左侧IPL与声调范畴感知的因果联系。实验1发现左侧IPL背侧通道不仅对声调范畴敏感, 范畴间比范畴内刺激对诱发了更强的氧合血红蛋白(HbO)浓度变化; 还对声学间隔敏感, 小声学间隔比大声学间隔刺激对诱发了更强的HbO浓度变化。实验2分别虚拟损伤左侧IPL的背侧和腹侧通道, 发现当左侧IPL背侧通道虚拟受损后, 该通道对声调范畴的敏感性消失, 而左侧IPL腹侧通道和前运动皮层通道对声学特征变得敏感。但是当左侧IPL腹侧通道虚拟受损后, 仅左侧额下回通道出现了功能代偿性地对声调范畴敏感。结果表明左侧IPL背侧在汉语声调范畴感知中起到重要作用, 而腹侧区域在语音感知的神经生理模型背侧通路中起着门控作用。研究结果从声调语言的角度丰富了语音感知加工的神经生理模型, 阐明了背侧/腹侧语音加工通路在范畴感知中的协作机制。

关键词: 语音范畴知觉, 声调, 顶下叶, fNIRS, TMS

Abstract: The left inferior parietal lobe (IPL) is a critical brain region for categorical perception of speech, and some studies have shown that it is involved in the categorical perception of Chinese tones. However, its specific role in tone perception remains unclear.
The current study manipulated both tonal categories (intercategory vs. intracategory) and acoustic features (large vs. small acoustic intervals) in successively presented stimulus pairs to examine whether the IPL is sensitive to acoustic features or to the abstract representation of tonal categories during Chinese tone perception. Experiment 1 used functional near-infrared spectroscopy (fNIRS) to localize functional activation in the IPL during tone perception. Experiment 2 used transcranial magnetic stimulation (TMS) to virtually impair the IPL and establish a causal neural link between the IPL and tonal categorical perception.
Experiment 1 showed that the dorsal IPL channel was sensitive to tonal categories, exhibiting more robust IPL activation induced by intercategory stimulation than intracategory stimulation. This region was also sensitive to acoustic intervals, with stronger activation induced by small acoustic intervals than by large ones. In Experiment 2, the dorsal and ventral IPL channels were virtually disrupted separately using TMS. When the dorsal IPL channel was inhibited, its sensitivity to tonal categories disappeared. In contrast, the ventral IPL channel and the left premotor cortex (PMC) channel were sensitive to acoustic intervals, with stronger activation induced by large acoustic intervals than by small ones. However, when TMS inhibited the ventral IPL channel, only functional compensation in the left inferior frontal gyrus channels showed sensitivity to tonal categories and induced greater intracategory activation than intercategory stimulation did.
In summary, these findings demonstrate a critical role of the left dorsal IPL in the categorical perception of Chinese tone. In contrast, the ventral IPL plays an essential gating role in the dorsal stream of speech perception. The results enrich the neurophysiological model of speech perception from a tonal language perspective, elucidating the collaborative mechanism between dorsal and ventral speech streams in categorical perception.

Key words: speech category, tone, inferior parietal lobule, fNIRS, TMS

中图分类号:

B842
B845

刘淑娟, 谭丽柔, 齐芸, 胡帅, 王小娟, 杨剑峰. (2026). 顶下叶在汉语声调感知中的作用：fNIRS导航的TMS研究. 心理学报, 58(7), 1343-1356.

LIU Shujuan, TAN Lirou, QI Yun, HU Shuai, WANG Xiaojuan, YANG Jianfeng. (2026). fNIRS-guided TMS technique reveals a critical role of the left inferior parietal lobule in Chinese tone perception. Acta Psychologica Sinica, 58(7), 1343-1356.

参考文献

[1] Al-Fahad R., Yeasin M., & Bidelman G.M. (2020). Decoding of single-trial EEG reveals unique states of functional brain connectivity that drive rapid speech categorization decisions.Journal of Neural Engineering, 17(1), 016045.
[2] Alho J., Green B. M., May P. J. C., Sams M., Tiitinen H., Rauschecker J. P., & Jääskeläinen I. P. (2016). Early-latency categorical speech sound representations in the left inferior frontal gyrus.Neuroimage, 129, 214-223.
[3] Brigadoi S., Ceccherini L., Cutini S., Scarpa F., Scatturin P., Selb J., ... Cooper R. J. (2014). Motion artifacts in functional near-infrared spectroscopy: A comparison of motion correction techniques applied to real cognitive data.Neuroimage, 85(Pt. 1), 181-191.
[4] Buchsbaum B. R., Hickok G., & Humphries C. (2001). Role of left posterior superior temporal gyrus in phonological processing for speech perception and production.Cognitive Science, 25(5), 663-678.
[5] Buchsbaum B. R., Olsen R. K., Koch P., & Berman K. F. (2005). Human dorsal and ventral auditory streams subserve rehearsal-based and echoic processes during verbal working memory.Neuron, 48(4), 687-697.
[6] Caplan D., Gow D., & Makris N. (1995). Analysis of lesions by MRI in stroke patients with acoustic-phonetic processing deficits.Neurology, 45(2), 293-298.
[7] Caspers S., Geyer S., Schleicher A., Mohlberg H., Amunts K., & Zilles K. (2006). The human inferior parietal cortex: Cytoarchitectonic parcellation and interindividual variability.Neuroimage, 33(2), 430-448.
[8] Chien P.-J., Friederici A. D., Hartwigsen G., & Sammler D. (2020). Neural correlates of intonation and lexical tone in tonal and non-tonal language speakers.Human Brain Mapping, 41(7), 1842-1858.
[9] Chien P.-J., Friederici A. D., Hartwigsen G., & Sammler D. (2021). Intonation processing increases task-specific fronto-temporal connectivity in tonal language speakers.Human Brain Mapping, 42(1), 161-174.
[10] Cohen, J. (1992). A power primer.Psychological Bulletin, 112(1), 155-159.
[11] Correia J. M., Jansma B. M. B., & Bonte M. (2015). Decoding articulatory features from fMRI responses in dorsal speech regions.Journal of Neuroscience, 35(45), 15015-15025.
[12] Faul F., Erdfelder E., Buchner A., & Lang A. G. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses.Behavior Research Methods, 41(4), 1149-1160.
[13] Feng G., Gan Z., Llanos F., Meng D., Wang S., Wong P. C. M., & Chandrasekaran B. (2021). A distributed dynamic brain network mediates linguistic tone representation and categorization.Neuroimage, 224, 117410.
[14] Feng G., Gan Z., Wang S., Wong P. C. M., & Chandrasekaran B. (2018). Task-general and acoustic-invariant neural representation of speech categories in the human brain.Cerebral Cortex, 28(9), 3241-3254.
[15] Gandour J., Dzemidzic M., Wong D., Lowe M., Tong Y., Hsieh L., ... Lurito J. (2003). Temporal integration of speech prosody is shaped by language experience: An fMRI study.Brain and Language, 84(3), 318-336.
[16] Gandour J., Tong Y., Wong D., Talavage T., Dzemidzic M., Xu Y., ... Lowe M. (2004). Hemispheric roles in the perception of speech prosody.Neuroimage, 23(1), 344-357.
[17] Hartwigsen G., Weigel A., Schuschan P., Siebner H. R., Weise D., Classen J., & Saur D. (2016). Dissociating parieto-frontal networks for phonological and semantic word decisions: A condition-and-perturb TMS study.Cerebral Cortex, 26(6), 2590-2601.
[18] Hickok G., Houde J., & Rong F. (2011). Sensorimotor integration in speech processing: Computational basis and neural organization.Neuron, 69(3), 407-422.
[19] Hickok, G., & Poeppel, D. (2007). The cortical organization of speech processing.Nature Reviews Neuroscience, 8(5), 393-402.
[20] Hsieh L., Gandour J., Wong D., & Hutchins G. D. (2001). Functional heterogeneity of inferior frontal gyrus is shaped by linguistic experience.Brain and Language, 76(3), 227-252.
[21] Huang Y. Z., Edwards M. J., Rounis E., Bhatia K. P., & Rothwell J. C. (2005). Theta burst stimulation of the human motor cortex.Neuron, 45(2), 201-206.
[22] Huppert T. J., Diamond S. G., Franceschini M. A., & Boas D. A. (2009). HomER: A review of time-series analysis methods for near-infrared spectroscopy of the brain.Applied Optics, 48(10), 280-298.
[23] Igelström K. M., Webb T. W., & Graziano, M. S. A. (2015). Neural processes in the human temporoparietal cortex separated by localized independent component analysis.Journal of Neuroscience, 35(25), 9432-9445.
[24] Joanisse M. F., Zevin J. D., & McCandliss B. D. (2007). Brain mechanisms implicated in the preattentive categorization of speech sounds revealed using fMRI and a short-interval habituation trial paradigm.Cerebral Cortex, 17(9), 2084-2093.
[25] Klein D., Zatorre R. J., Milner B., & Zhao V. (2001). A cross-linguistic PET study of tone perception in mandarin Chinese and English speakers.Neuroimage, 13(4), 646-653.
[26] Kwok V. P. Y., Dan G., Yakpo K., Matthews S., & Tan L. H. (2016). Neural systems for auditory perception of lexical tones.Journal of Neurolinguistics, 37, 34-40.
[27] Kwok V. P. Y., Matthews S., Yakpo K., & Tan L. H. (2019). Neural correlates and functional connectivity of lexical tone processing in reading.Brain and Language, 196, 104662.
[28] Kwok V. P. Y., Wang T., Chen S., Yakpo K., Zhu L., Fox P. T., & Tan L. H. (2015). Neural signatures of lexical tone reading.Human Brain Mapping, 36(1), 304-312.
[29] Lawrence R. J., Wiggins I. M., Anderson C. A., Davies- Thompson J., & Hartley, D. E. H. (2018). Cortical correlates of speech intelligibility measured using functional near- infrared spectroscopy (fNIRS).Hearing Research, 370, 53-64.
[30] Li Y., Tang C., Lu J., Wu J., & Chang E. F. (2021). Human cortical encoding of pitch in tonal and non-tonal languages.Nature Communications, 12(1), 1161.
[31] Liang, B., & Du, Y. (2018). The functional neuroanatomy of lexical tone perception: An activation likelihood estimation meta-analysis.Frontiers in Neuroscience, 12, 495.
[32] Liang B., Li Y., Zhao W., & Du Y. (2023). Bilateral human laryngeal motor cortex in perceptual decision of lexical tone and voicing of consonant.Nature Communications, 14(1), 4710.
[33] Luo H., Ni J. T., Li Z. H., Li X. O., Zhang D. R., Zeng F. G., & Chen L. (2006). Opposite patterns of hemisphere dominance for early auditory processing of lexical tones and consonants.Proceedings of the National Academy of Sciences of the United States of America, 103(51), 19558-19563.
[34] Mahmud M. S., Yeasin M., & Bidelman G. M. (2021). Data-driven machine learning models for decoding speech categorization from evoked brain responses.Journal of Neural Engineering, 18(4), 046012.
[35] Michaelis K., Miyakoshi M., Norato G., Medvedev A. V., & Turkeltaub P. E. (2021). Motor engagement relates to accurate perception of phonemes and audiovisual words, but not auditory words.Communications Biology, 4(1), 108.
[36] Murakami T., Kell C. A., Restle J., Ugawa Y., & Ziemann U. (2015). Left dorsal speech stream components and their contribution to phonological processing.Journal of Neuroscience, 35(4), 1411-1422.
[37] Osnes B., Hugdahl K., & Specht K. (2011). Effective connectivity analysis demonstrates involvement of premotor cortex during speech perception.Neuroimage, 54(3), 2437-2445.
[38] Peng G., Zheng H. Y., Gong T., Yang R. X., Kong J. P., & Wang, W. S. Y. (2010). The influence of language experience on categorical perception of pitch contours.Journal of Phonetics, 38(4), 616-624.
[39] Pinti P., Tachtsidis I., Hamilton A., Hirsch J., Aichelburg C., Gilbert S., & Burgess P. W. (2020). The present and future use of functional near-infrared spectroscopy (fNIRS) for cognitive neuroscience.Annals of the New York Academy of Sciences, 1464(1), 5-29.
[40] Preisig B. C., Riecke L., & Hervais-Adelman A. (2022). Speech sound categorization: The contribution of non-auditory and auditory cortical regions.Neuroimage, 258, 119375.
[41] Rauschecker, J. P., & Scott, S. K. (2009). Maps and streams in the auditory cortex: Nonhuman primates illuminate human speech processing.Nature Neuroscience, 12(6), 718-724.
[42] Rogalsky C., Basilakos A., Rorden C., Pillay S., LaCroix A. N., Keator L., ... Hickok G. (2022). The neuroanatomy of speech processing: A large-scale lesion study. Journal of Cognitive Neuroscience, 34(8), 1355-1375.
[43] Saur D., Kreher B. W., Schnell S., Kümmerer D., Kellmeyer P., Vry M. S., ... Weiller C. (2008). Ventral and dorsal pathways for language. Proceedings of the National Academy of Sciences of the United States of America, 105(46), 18035-18040.
[44] Shen, G., & Froud, K. (2016). Categorical perception of lexical tones by English learners of Mandarin Chinese. TheJournal of the Acoustical Society of America, 140(6), 4396-4403.
[45] Si X., Zhou W., & Hong B. (2017). Cooperative cortical network for categorical processing of Chinese lexical tone.Proceedings of the National Academy of Sciences of the United States of America, 114(46), 12303-12308.
[46] Stoeckel, M. C., & Binkofski, F. (2010). The role of ipsilateral primary motor cortex in movement control and recovery from brain damage.Experimental Neurology, 221(1), 13-17.
[47] Tian F. H., Lin Z.-J., & Liu H. L. (2013). EasyTopo: A toolbox for rapid diffuse optical topography based on a standard template of brain atlas.Proceedings of the Society of Photo-Optical Instrumentation Engineers, 8578, 458-467.
[48] Valbret H., Moulines E., & Tubach J. P. (1992). Voice transformation using PSOLA technique.Speech Communication, 11(2-3), 175-187.
[49] Wan N., Hancock A. S., Moon T. K., & Gillam R. B. (2018). A functional near-infrared spectroscopic investigation of speech production during reading.Human Brain Mapping, 39(3), 1428-1437.
[50] Wang J., Fan L., Zhang Y., Liu Y., Jiang D., Zhang Y., ... Jiang T. (2012). Tractography-based parcellation of the human left inferior parietal lobule.Neuroimage, 63(2), 641-652.
[51] Wang Y., Sereno J. A., Jongman A., & Hirsch J. (2003). fMRI evidence for cortical modification during learning of Mandarin lexical tone.Journal of Cognitive Neuroscience, 15(7), 1019-1027.
[52] Wild C. J., Yusuf A., Wilson D. E., Peelle J. E., Davis M. H., & Johnsrude I. S. (2012). Effortful listening: The processing of degraded speech depends critically on attention.Journal of Neuroscience, 32(40), 14010-14021.
[53] Wong P. C. M., Parsons L. M., Martinez M., & Diehl R. L. (2004). The role of the insular cortex in pitch pattern perception: The effect of linguistic contexts.Journal of Neuroscience, 24(41), 9153-9160.
[54] Wong P. C. M., Perrachione T. K., & Parrish T. B. (2007). Neural characteristics of successful and less successful speech and word learning in adults.Human Brain Mapping, 28(10), 995-1006.
[55] Xi J., Zhang L., Shu H., Zhang Y., & Li P. (2010). Categorical perception of lexical tones in Chinese revealed by mismatch negativity. Neuroscience, 170(1), 223-231.
[56] Xu Y., Gandour J. T., & Francis A. L. (2006). Effects of language experience and stimulus complexity on the categorical perception of pitch direction. Journal of the Acoustical Society of America, 120(2), 1063-1074.
[57] Yang J., Gates K. M., Molenaar P., & Li P. (2015). Neural changes underlying successful second language word learning: An fMRI study.Journal of Neurolinguistics, 33, 29-49.
[58] Yang, Q., & Chen, Y. (2022). Phonological competition in Mandarin spoken word recognition.Language, Cognition and Neuroscience, 37(7), 820-843.
[59] Ye J. C., Tak S., Jang K. E., Jung J., & Jang J. (2009). NIRS-SPM: Statistical parametric mapping for near-infrared spectroscopy.Neuroimage, 44(2), 428-447.
[60] Yu K., Wang R., Li L., & Li P. (2014). Processing of acoustic and phonological information of lexical tones in Mandarin Chinese revealed by mismatch negativity.Frontiers in Human Neuroscience, 8, 729.
[61] Zhang L., Xi J., Wu H., Shu H., & Li P. (2012). Electrophysiological evidence of categorical perception of Chinese lexical tones in attentive condition.Neuroreport, 23(1), 35-39.
[62] Zhang L., Xi J., Xu G. Q., Shu H., Wang X., & Li P. (2011). Cortical dynamics of acoustic and phonological processing in speech perception.Plos One, 6(6), e20963.
[63] Zhao R., Wang X., & Yang J. (2016). The role of tone in Chinese syllable perception.Acta Psychologica Sinica, 48(8), 915-923.
[赵荣, 王小娟, 杨剑峰. (2016). 声调在汉语音节感知中的作用.心理学报, 48(8), 915-923.]
[64] Zinszer B. D., Chen P., Wu H., Shu H., & Li P. (2015). Second language experience modulates neural specialization for first language lexical tones.Journal of Neurolinguistics, 33, 50-66.