ISSN 1671-3710
CN 11-4766/R
主办:中国科学院心理研究所
出版:科学出版社

心理科学进展 ›› 2015, Vol. 23 ›› Issue (10): 1789-1798.doi: 10.3724/SP.J.1042.2015.01789

• 研究前沿 • 上一篇    下一篇

经颅直流电刺激在抑郁症治疗中的应用

张大山;史慧颖;刘威;邱江;范丰慧   

  1. (认知与人格教育部重点实验室(西南大学); 西南大学心理学部, 重庆 400715)
  • 收稿日期:2014-12-04 出版日期:2015-10-15 发布日期:2015-10-15
  • 通讯作者: 史慧颖, E-mail: youle@swu.edu.cn 邱江, E-mail: qiuj318@swu.edu.cn
  • 基金资助:

    重庆市人文社会科学重点研究基地项目(09SKB24);中央高校基本科研业务费专项资金资助(SWU1109060);国家自然科学基金项目(NSFC31070900; NSFC31170983; NSFC31271087)

The Application of Transcranial Direct Current Stimulation (tDCS) in the Treatment of Depression

ZHANG Dashan; SHI Huiying; LIU Wei; QIU Jiang; FAN Fenghui   

  1. (Key Laboratory of Cognition and Personality (SWU), Ministry of Education;
    School of Psychology,Southwest University, Chongqing 400715, China)
  • Received:2014-12-04 Online:2015-10-15 Published:2015-10-15
  • Contact: SHI Huiying, E-mail: youle@swu.edu.cn QIU Jiang, E-mail: qiuj318@swu.edu.cn

摘要:

已有的神经影像学研究成果揭示, 抑郁症发作的重要原因之一是大脑前额叶皮层结构和功能受损。经颅直流电刺激(tDCS)作为一种无创脑刺激, 选取前额叶皮层作为刺激区域, 通过调节皮层兴奋性来治疗抑郁症, 能够有效缓解抑郁症状和改善受损的认知功能, 疗效明显且持久稳定。针对tDCS在抑郁症治疗研究中的问题, 未来可从有效性、个体差异以及预防干预等六个方面进一步研究, 以期tDCS作为一种具有潜力的治疗手段, 在临床上有更为广泛地应用。

关键词: 抑郁症, 背外侧前额叶皮层, 经颅直流电刺激(tDCS), 治疗

Abstract:

Previous neuroimaging researches proposed that one of the most important etiologies of depression is the impairment of structure and function of the prefrontal cortex. As a non-invasive technique, tDCS can alleviate depressive symptoms and improve impaired cognitive functions steadily and effectively by regulating cortical excitability through targeting at the prefrontal cortex. To achieve more extensive clinical application in the future, future studies should do more advanced researches from six orientations, such as the effectiveness of tDCS, individual differences, early prevention and intervention.

Key words: depression, dorsolateral prefrontal cortex, transcranial direct current stimulation (tDCS), treatment