抑郁症情绪失调的动态特征：情绪动力学的视角

doi:10.3724/SP.J.1042.2024.00364

摘要/Abstract

摘要：

抑郁症在DSM-5中界定的核心特征是持久的情绪紊乱, 如过度悲伤和急剧减少的愉悦情绪体验。近年来, 情绪动力学强调: 抑郁症临床人群的情绪失调不局限于较高的消极情绪平均强度和较低的积极情绪平均强度, 还表现为异常的情绪动态模式。本综述系统地纳入18篇采用生态瞬时评估探究日常生活中抑郁症临床人群的情绪动态特征的文献, 结果表明: 1) 相比于健康对照组, 抑郁症患者消极情绪波动幅度更大, 表现为更大的消极情绪变异性和消极情绪不稳定性。2) 抑郁症患者的情绪系统僵化且缺乏灵活性, 表现为更大的消极情绪惯性和更密集的情绪网络。3) 抑郁症患者情绪反应性存在异常, 表现为经历积极事件后的心境点亮效应, 经历消极事件后更大的消极情绪反应性。4) 患者情绪系统的复杂度下降, 表现为更低的情绪分化水平。处于抑郁症缓解期的个体也表现出一定程度的情绪失调。本综述首次从情绪动力学的视角总结了抑郁症情绪失调的特征, 这些情绪动态特征为抑郁症的个体化医疗和复发预防提供了潜在的、具有高生态效度的干预靶点。

关键词: 抑郁症, 情绪动力学, 情绪失调, 生态瞬时评估

Abstract:

The core feature of major depressive disorder, as defined in the DSM-5, is persistent mood disturbances characterized by excessive sadness and significantly reduced pleasant emotional experiences. Previous studies explored the emotion dysregulation of major depressive disorder by examining the static and trait-related aspects of overall emotional intensity, based on the trait model of personality. However, in real-life contexts, an individual's emotional experiences are not static but dynamically fluctuate in response to intricate social situations. Emotion is a dynamic process influenced by social interaction, individual evaluation processes and the external environment. Emotion dynamics consider the temporal dimension and volatility as the intrinsic features of emotions, to investigate how micro-level emotional fluctuation patterns impact psychological well-being at the macro-level. Researches on emotion dynamics have emphasized that the emotion dysregulation in major depressive disorder goes beyond increased negative emotional intensity and decreased positive emotional intensity. It also manifests as abnormal emotional dynamic patterns, specifically characterized by deviations in indicators of emotion dynamic such as emotion variability, instability, inertia, and others. Therefore, the objective of this systematic review is to summarize the dynamic features of emotion dysregulation in major depression from the perspective of emotion dynamics.

This systematic review conducted a comprehensive search of the Web of Science, PubMed, Scopus, and PsycInfo databases from January 1, 2013 to January 1, 2023. A total of 18 studies were included in this review, which utilized ecological momentary assessment to explore the differences in indicators of emotion dynamics between clinical populations with depression and the control group. Consistent with findings from traditional cross-sectional retrospective studies and laboratory research, studies based on ecological momentary assessment indicated that patients with depression experience higher average intensity of negative emotions and lower average intensity of positive emotions in their daily lives. Significantly, this review offered a more nuanced understanding of emotion dysregulation in major depressive disorder beyond average emotional intensity. The key findings were as follows: (1) Patients with depression had greater negative emotion fluctuations compared with the healthy control group. These fluctuations manifested as greater negative emotion variability and instability. Compared to the healthy control group, individuals with depression exhibited a greater overall fluctuation in negative emotional experiences in their daily lives, with more pronounced fluctuations between two consecutive time points. (2) Depressed patients exhibited a rigid and inflexible emotional system, characterized by greater negative emotion inertia and denser emotion networks. Compared to the healthy control group, individuals with depression exhibited a greater tendency for negative emotions experienced in the past to persist into the next moment. Depressed patients had a greater number of connections and stronger linkages between nodes in their emotional networks. (3) Depressed patients exhibited abnormalities in emotional reactivity. This was reflected as the mood brightening effect after positive events and greater negative emotion reactivity after negative events. Compared to the healthy control group, individuals with depression exhibited greater emotional improvement following positive events and greater increase in negative emotions following negative events. (4) Patients with depression experienced decreased complexity in their emotional system. This manifested as a lower level of emotion differentiation. Compared to the control group, individuals with depression tended to perceive and report emotions in a relatively simplistic and generalized manner, lacking the ability to differentiate subtle distinctions between discrete emotions. Furthermore, patients with remitted depression also exhibited some degree of emotion dysregulation, providing empirical support for the complications or scar model and the set-point theory.

This review was the first to comprehensively elucidate the primary features of emotion dysregulation in major depressive disorder viewed from emotion dynamics. The findings of this review provided further theoretical support for recent dynamic models of mental disorders, including complex dynamical system theory and network theory. Research in clinical psychology might benefit from accurately modeling the dynamic feature of psychopathology and approaching psychopathology as a system. As for clinical practice, the results contributed to the identification of potential intervention targets with high ecological validity for individualized treatment and relapse prevention of depression. In accordance with the principles of personalized medicine, psychiatrists could target specific features of a patient's emotion dysregulation as focal points for tailored and precise interventions, thereby enhancing the effective remission rates of depression. Furthermore, the insights from an emotion dynamics perspective inspired clinical practitioners to utilize more digitized and intelligent tools, such as smartphones and wearable devices, for advancing clinical assessments and treatments in the realm of mental disorders. This ongoing progress contributed to innovation and development in remote mental health services within the digital age.

Key words: major depressive disorder, emotion dynamics, emotion dysregulation, ecological momentary assessment

中图分类号:

R749.4

吴朝毅, 王振. (2024). 抑郁症情绪失调的动态特征：情绪动力学的视角. 心理科学进展 , 32(2), 364-385.

WU Chaoyi, WANG Zhen. (2024). The dynamic features of emotion dysregulation in major depressive disorder: An emotion dynamics perspective. Advances in Psychological Science, 32(2), 364-385.

图/表 4

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情绪动态特征	定义	数学表达式/统计模型参数	时间依赖性	参考文献
1. 情绪均值 (Mean)	个体在一段时间内情绪的平均强度	个体内水平所有情绪观测值的均值。 \[{{M}_{i}}=\frac{1}{{{N}_{i}}}\sum\limits_{j=1}^{{{N}_{i}}}{{{x}_{i,j}}}\]	无	Clark & Tellegen, 1988; Watson & Tellegen, 1985)
2. 情绪变异性 (Variability)	个体在一段时间内情绪体验的整体变化幅度	一段时间内所有情绪观测值的个体内标准差。 \[SD=\sqrt{\frac{\sum{{{({{X}_{i}}-\bar{X})}^{2}}}}{n-1}}\]	无	(Jahng et al., 2008)
3. 情绪不稳定性 (Instability)	个体在连续2个时间点之间的情绪波动幅度或情绪剧变概率	MSSD: 连续2个时间点的情绪观测值X_i和X_i+1的平方差的均值(部分研究采用RMSSD, 即将MSSD开平方根)。 \[MSSD=\frac{1}{N-1}\sum\limits_{i=1}^{N-1}{{{({{x}_{i+1}}-{{x}_{i}})}^{2}}}\]	有	(Jahng et al., 2008)
3. 情绪不稳定性 (Instability)	个体在连续2个时间点之间的情绪波动幅度或情绪剧变概率	AC)的概率。AC通常设定为样本第90百分位数等。 \[PAC=\frac{1}{N-1}\sum\limits_{i=1}^{N-1}{A}{{C}_{i+1}}\]	有	(Jahng et al., 2008)
4. 相对变异指数 (Relative Variability Index)	控制和修正变异性、不稳定性指标和均值之间的统计依赖关系	将原来的变异性、不稳定性统计量V_i除以个体i 给定均值M_i后的最大可能的变异性max (V_i \| M_i)。修正后的指标常用SD、MSSD表示。 \[V_{i}^{*}=\frac{{{V}_{i}}}{\max ({{V}_{i}}\mid {{M}_{i}})}\]	SD无 MSSD 有	(Mestdagh et al., 2018)
5. 情绪惯性 (Inertia)	个体当前的情绪状态多大程度上可以被之前的情绪状态所预测	多水平模型中情绪的自回归系数。例如, 消极情绪惯性是个体内水平t−1时间测的NA ^(w)_t−1预测t时间测的NA ^(w)_t的回归系数Φ_NN。	有	(Hamaker et al., 2018; Jahng et al., 2008; Kuppens et al., 2010)
6. 情绪反应性 (Reactivity)	个体响应外部事件所产生的情绪变化	多水平模型中上个时间点的情绪事件预测当下情绪的回归系数。对消极事件的消极情绪反应性为个体内水平t时间测的上个时间点的NE ^(w)_t(条目描述是“从上次测量到现在的情绪事件”, 条目本身具有时间滞后性)预测t时间测的当下的NA ^(w)_t的回归系数β_NE。	有	(Booij et al., 2018; Grosse Rueschkamp et al., 2020; Sperry & Kwapil, 2019)
7. 情绪网络密度 (Network Density)	个体当下的特定情绪如何受上个时间点各种情绪的影响	通过网络分析建立一系列多水平VAR模型, 模型中t时间的特定情绪被t−1时间点的所有情绪(包括特定情绪自身)所预测。计算该个体所有回归系数的绝对值的均值。	有	(Bringmann et al., 2016; Pe et al., 2015; Shin et al., 2022)
8. 情绪分化 (Differentiation)	个体区别多种离散情绪的能力	通过ICC计算相同效价下多种情绪之间的组内相关系数, ICC越小代表情绪分化水平越高。	无	Liu, et al., 2021)

情绪动态特征	定义	数学表达式/统计模型参数	时间依赖性	参考文献
1. 情绪均值 (Mean)	个体在一段时间内情绪的平均强度	个体内水平所有情绪观测值的均值。 \[{{M}_{i}}=\frac{1}{{{N}_{i}}}\sum\limits_{j=1}^{{{N}_{i}}}{{{x}_{i,j}}}\]	无	Clark & Tellegen, 1988; Watson & Tellegen, 1985)
2. 情绪变异性 (Variability)	个体在一段时间内情绪体验的整体变化幅度	一段时间内所有情绪观测值的个体内标准差。 \[SD=\sqrt{\frac{\sum{{{({{X}_{i}}-\bar{X})}^{2}}}}{n-1}}\]	无	(Jahng et al., 2008)
3. 情绪不稳定性 (Instability)	个体在连续2个时间点之间的情绪波动幅度或情绪剧变概率	MSSD: 连续2个时间点的情绪观测值X_i和X_i+1的平方差的均值(部分研究采用RMSSD, 即将MSSD开平方根)。 \[MSSD=\frac{1}{N-1}\sum\limits_{i=1}^{N-1}{{{({{x}_{i+1}}-{{x}_{i}})}^{2}}}\]	有	(Jahng et al., 2008)
3. 情绪不稳定性 (Instability)	个体在连续2个时间点之间的情绪波动幅度或情绪剧变概率	AC)的概率。AC通常设定为样本第90百分位数等。 \[PAC=\frac{1}{N-1}\sum\limits_{i=1}^{N-1}{A}{{C}_{i+1}}\]	有	(Jahng et al., 2008)
4. 相对变异指数 (Relative Variability Index)	控制和修正变异性、不稳定性指标和均值之间的统计依赖关系	将原来的变异性、不稳定性统计量V_i除以个体i 给定均值M_i后的最大可能的变异性max (V_i \| M_i)。修正后的指标常用SD、MSSD表示。 \[V_{i}^{*}=\frac{{{V}_{i}}}{\max ({{V}_{i}}\mid {{M}_{i}})}\]	SD无 MSSD 有	(Mestdagh et al., 2018)
5. 情绪惯性 (Inertia)	个体当前的情绪状态多大程度上可以被之前的情绪状态所预测	多水平模型中情绪的自回归系数。例如, 消极情绪惯性是个体内水平t−1时间测的NA ^(w)_t−1预测t时间测的NA ^(w)_t的回归系数Φ_NN。	有	(Hamaker et al., 2018; Jahng et al., 2008; Kuppens et al., 2010)
6. 情绪反应性 (Reactivity)	个体响应外部事件所产生的情绪变化	多水平模型中上个时间点的情绪事件预测当下情绪的回归系数。对消极事件的消极情绪反应性为个体内水平t时间测的上个时间点的NE ^(w)_t(条目描述是“从上次测量到现在的情绪事件”, 条目本身具有时间滞后性)预测t时间测的当下的NA ^(w)_t的回归系数β_NE。	有	(Booij et al., 2018; Grosse Rueschkamp et al., 2020; Sperry & Kwapil, 2019)
7. 情绪网络密度 (Network Density)	个体当下的特定情绪如何受上个时间点各种情绪的影响	通过网络分析建立一系列多水平VAR模型, 模型中t时间的特定情绪被t−1时间点的所有情绪(包括特定情绪自身)所预测。计算该个体所有回归系数的绝对值的均值。	有	(Bringmann et al., 2016; Pe et al., 2015; Shin et al., 2022)
8. 情绪分化 (Differentiation)	个体区别多种离散情绪的能力	通过ICC计算相同效价下多种情绪之间的组内相关系数, ICC越小代表情绪分化水平越高。	无	Liu, et al., 2021)

N	抑郁组	对照组	EMA	情绪条目	与抑郁症情绪动态特征相关的研究结果	文献
1	伴快感缺失MDD患者(47)	健康对照 (40)	10×7	PA: euphoric, happy, relaxed	与健康对照组相比, 伴有快感缺失的MDD患者PA均值更小, 但PA变异性、PA不稳定性、PA惯性、PA反应性没有显著差异。	(Heininga et al., 2019)
2	1. MDD/AD患者(95) 2. MDD/AD缓解期个体(178)	健康对照 (92)	5×14	PA: satisfied, relaxed, cheerful, energetic, enthusiastic, calm NA: upset, irritated, listless, down, nervous, bored, anxious	1. MDD/AD患者PA和NA的不稳定性(RMSSD)和变异性, 以及NA均值和惯性最大, 其次是缓解期个体, 最后是健康对照组。 2. MDD/AD患者PA均值最小, 其次是缓解期个体, 健康对照组PA均值最大。 3. MDD/AD患者和缓解期个体的PA情绪惯性没有显著差异, 都大于健康对照组。 4.采用RMSSD控制情绪均值的效应后, 三个组别的情绪不稳定性*的组间差异仍显著, 但MDD/AD患者和缓解期个体之间的差异不再显著。	(Schoevers et al., 2021)
3	1. MDD患者(26) 2. MDD缓解期个体(82)	健康对照 (471)	10×5	PA: cheerful, content, energetic, enthusiastic NA: insecure, lonely, anxious, low, guilty, suspicious	1.与健康对照组相比, MDD患者过夜的NA惯性更大。 2.与健康对照组相比, 缓解期的个体日间的NA惯性更大。 3.过夜的NA惯性与睡眠时长和质量的关系在不同组别存在差异。	(Minaeva et al., 2021)
4	MDD患者 (53)	健康对照 (53)	8×7	PA: happy, excited, alert, active NA: sad, anxious, angry, frustrated, ashamed, disgusted, guilty	MDD患者整体的情绪网络更密集, 并且这种差异源于NA网络密度而非PA网络密度的差异。	(Pe et al., 2015)
5	1. MDD患者(48) 2. MDD缓解期个体(80)	健康对照 (87)	5×14	PA: relaxed, content, calm, happy, excited, enthusiastic NA: bored, sluggish, sad, frustrated, nervous, angry	1. MDD患者的NA均值大于处于缓解期的个体, 处于缓解期的个体的NA均值大于健康对照组。 2. MDD患者的PA均值小于处于缓解期的个体和健康对照组, 处于缓解期的个体和健康对照组的PA均值没有显著差异。 3. 与健康对照组相比, MDD患者和处于缓解期的个体NA和PA的情绪分化水平更低, MDD患者和缓解期个体的情绪分化水平没有显著差异。	Liu, et al., 2021)
6	MDD患者 (40)	健康对照 (40)	10×4	PA: joy, even temper, satisfaction NA: sadness, fear, anger, rage, guilt, shame, disgust	1.与健康对照组相比, MDD患者NA均值更大, PA均值更小, NA惯性和NA变异性更大。 2.与健康对照组相比, MDD患者经历积极事件后表现出心境点亮效应(更大程度的NA减少)。 3.与健康对照组相比, MDD患者NA情绪不稳定性更大。但控制情绪变异性的效应后, 这两个组别的组间差异不显著。	(J. Nelson et al., 2020)
7	1. MDD患者(48) 2. MDD缓解期个体(80)	健康对照 (87)	5×14	PA: relaxed, content, calm, happy, excited, enthusiastic NA: bored, sluggish, sad, frustrated, nervous, angry	1. MDD患者的NA均值和NA变异性最大, 健康对照组最小, 处于缓解期的个体介于两者之间。控制NA均值后, NA变异性的组间差异仍显著。 2. 3个组别NA惯性的组间差异不显著。 3. 对于PA的情绪动力指标而言, 只有PA均值在3个组别的组间差异显著。抑郁症患者的PA均值小于处于缓解期的个体和健康对照组, 而处于缓解期的个体和健康对照组的PA均值没有显著差异。	& English, 2021)
8	具有MDD终身诊断的患者(116), 其中40.5%当前被诊断为MDD	1. 健康对照(65) 2. 双相障碍I型(33) 3. 双相障碍II型(37) 4. 焦虑障碍(36)	4×14	效价: very happy (1) to very sad (7) 唤醒程度: very calm (1) to very anxious (7)	1.与健康对照组相比, 具有MDD终身诊断的患者悲伤、焦虑情绪的均值和焦虑情绪的变异性, 以及悲伤、焦虑情绪的不稳定性更大。 2.经历积极事件后, 具有MDD终身诊断的患者(相比健康对照组)表现出心境点亮效应(更大程度的焦虑情绪减少)。经历消极事件后, 具有MDD终身诊断的患者表现出更大的NA情绪反应性(更大程度的焦虑情绪增加)。 3.进一步将具有MDD终身诊断的患者细分为当下患有MDD的患者、处于缓解期的个体两个组别后, 两个组别的情绪反应性没有显著差异。	(Lamers et al., 2018)
9	MDD患者且共病BPD (20)	MDD患者没有共病BPD (21)	5×7	PA: happy, content, relaxed NA: sad, anxious, angry, empty, lonely, guilty, tense	1.共病BPD和不共病BPD的两组MDD患者在情绪不稳定性, 以及与他人积极互动/与他人消极互动/感知到被拒绝/感知到失败后的总体情绪反应性上没有组间差异。 2.相比于不共病BPD的MDD患者, 共病BPD的MDD患者在经历了独自一人的事件后体验到了更大的情绪反应性(更大程度的总体情绪恶化)。	(Köhling et al., 2016)
10	1. 患MDD的大一学生(23) 2. 缓解期的大一学生(42)	无MDD病史的大一学生(43)	4×14	NA: sad, alone, angry with self, guilty, lonely, hopeless	1. 相比于处于缓解期和无MDD病史的个体, MDD患者对于日常感知到的压力表现出更大的NA情绪反应性(更大程度的NA增加)。 2. MDD患者对人际消极事件表现出更大的NA情绪反应性(更大程度的NA增加), 而处于缓解期和无MDD病史的个体对人际或非人际的消极事件的情绪反应性没有显著差异。	(Sheets & Armey, 2020)
11	MDD患者(30), 治疗后分为: 1.症状缓解组(11) 2.症状没有缓解组(19)	健康对照 (39)	10×6	PA: energetic, enthusiastic, happy, cheerful, talkative, strong, satisfied, self-assured NA: anxious, irritated, restless, tense, guilty, edgy, distractible, agitated	1.相比于健康对照组和缓解期组, 症状未缓解的MDD患者对事件、活动和社交这三种应激源的NA情绪反应性更大(更大程度的NA增加)。 2.缓解期组和健康对照组在对事件和活动应激源的情绪反应性上没有组间差异, 但是缓解期组(相对于健康对照组)仍表现出对社交应激源更大的NA情绪反应性(更大程度的NA增加)。	(van Winkel et al., 2015)
12	MDD或GAD患者(61)	健康对照(58)	9×8	PA: relaxed, content, excited, enthusiastic NA: angry, tired, irritable, anxious, depressed	基于EMA得到的NA和PA的网络密度都在人口学特征和情绪均值、标准差之上显著预测个体的诊断状态。具体而言, 更大的NA情绪网络密度、更小的PA情绪网络密度与MDD/GAD的诊断存在相关。	(Shin et al., 2022)
13	处于复发性MDD缓解期的个体(51)	健康对照(51)	10×5	PA: cheerful, energetic, enthusiastic, satisfied, relaxed, calm NA: upset, irritated, nervous, listless, down, bored	1.处于复发性MDD缓解期的个体(相比于健康对照组)在经历消极日常事件后表现出更大的NA情绪反应性(更大程度的NA增加)。 2.处于复发性MDD缓解期的个体(相比于健康对照组)在经历积极日常事件后表现出心境点亮效应(更大程度的PA增加和更大程度的NA减少)。	(Schricker et al., 2022)
14	1.MDD不共病GAD (38) 2.MDD共病GAD (38)	1.GAD, 且不共病MDD (36) 2.健康对照(33)	8×7	PA: happy, proud, determined NA: sad, anxious, dissatisfied with myself	1.MDD不共病GAD组和MDD共病GAD组的患者(相比于健康对照组)在经历积极事件后都表现出心境点亮效应 (更大程度的PA增加和更大程度的NA减少)。 2.患者基线抑郁症状越严重, 心境点亮效应更强。 3.与GAD相比, MDD对积极事件的情绪反应性改变更具有特异性。	(Khazanov et al., 2019)
15	MDD患者(31)	健康对照 (33)	10×6	PA: happy, relaxed, interested, enjoying myself NA: irritated, down, anxious, tense, ashamed, guilty	1. 相比于健康对照组, MDD患者表现出更大的NA和PA的情绪变异性和不稳定性。 2. MDD患者和健康对照组在日间积极情绪的时间趋势上存在差异, MDD患者每天积极情绪随时间的变化呈现为倒U型, 而健康对照组呈现为正向的线性趋势。	(Crowe et al., 2019)
16	MDD患者(41)	健康对照 (33)	10×3	DA: depressed, sad	相比于健康对照组, MDD患者在经历日常积极事件后表现出心境点亮效应(更大程度的烦躁情绪减少)。	(Panaite et al., 2018)
17	DD患者(38)	BPD患者(67)	6×28	NA: fear (6 items) hostility (6 items) sadness (5 items) 详见(Watson & Clark, 1994)	1. DD患者NA情绪分化水平高于BPD患者。 2. NA情绪分化水平可以负向预测冲动性, 但预测的效应在DD患者和BPD患者两个组别中没有显著差异。	(Tomko et al., 2015)
18	有MDD既往诊断史, 且目前轻度抑郁的患者(129)	1. 健康对照(207) 2. 精神病性障碍患者(263)	10× (5/6)	PA: cheerful, content NA: insecure, down, suspicious	1.相比于精神病性障碍组和健康对照组, 抑郁症患者的情绪状态网络的节点间的联系最为紧密。 2.相比于精神病性障碍组, 抑郁症患者的网络结构表现出更多的积极和消极心理状态之间的特异性联系。	(Wigman et al., 2015)

N	抑郁组	对照组	EMA	情绪条目	与抑郁症情绪动态特征相关的研究结果	文献
1	伴快感缺失MDD患者(47)	健康对照 (40)	10×7	PA: euphoric, happy, relaxed	与健康对照组相比, 伴有快感缺失的MDD患者PA均值更小, 但PA变异性、PA不稳定性、PA惯性、PA反应性没有显著差异。	(Heininga et al., 2019)
2	1. MDD/AD患者(95) 2. MDD/AD缓解期个体(178)	健康对照 (92)	5×14	PA: satisfied, relaxed, cheerful, energetic, enthusiastic, calm NA: upset, irritated, listless, down, nervous, bored, anxious	1. MDD/AD患者PA和NA的不稳定性(RMSSD)和变异性, 以及NA均值和惯性最大, 其次是缓解期个体, 最后是健康对照组。 2. MDD/AD患者PA均值最小, 其次是缓解期个体, 健康对照组PA均值最大。 3. MDD/AD患者和缓解期个体的PA情绪惯性没有显著差异, 都大于健康对照组。 4.采用RMSSD控制情绪均值的效应后, 三个组别的情绪不稳定性*的组间差异仍显著, 但MDD/AD患者和缓解期个体之间的差异不再显著。	(Schoevers et al., 2021)
3	1. MDD患者(26) 2. MDD缓解期个体(82)	健康对照 (471)	10×5	PA: cheerful, content, energetic, enthusiastic NA: insecure, lonely, anxious, low, guilty, suspicious	1.与健康对照组相比, MDD患者过夜的NA惯性更大。 2.与健康对照组相比, 缓解期的个体日间的NA惯性更大。 3.过夜的NA惯性与睡眠时长和质量的关系在不同组别存在差异。	(Minaeva et al., 2021)
4	MDD患者 (53)	健康对照 (53)	8×7	PA: happy, excited, alert, active NA: sad, anxious, angry, frustrated, ashamed, disgusted, guilty	MDD患者整体的情绪网络更密集, 并且这种差异源于NA网络密度而非PA网络密度的差异。	(Pe et al., 2015)
5	1. MDD患者(48) 2. MDD缓解期个体(80)	健康对照 (87)	5×14	PA: relaxed, content, calm, happy, excited, enthusiastic NA: bored, sluggish, sad, frustrated, nervous, angry	1. MDD患者的NA均值大于处于缓解期的个体, 处于缓解期的个体的NA均值大于健康对照组。 2. MDD患者的PA均值小于处于缓解期的个体和健康对照组, 处于缓解期的个体和健康对照组的PA均值没有显著差异。 3. 与健康对照组相比, MDD患者和处于缓解期的个体NA和PA的情绪分化水平更低, MDD患者和缓解期个体的情绪分化水平没有显著差异。	Liu, et al., 2021)
6	MDD患者 (40)	健康对照 (40)	10×4	PA: joy, even temper, satisfaction NA: sadness, fear, anger, rage, guilt, shame, disgust	1.与健康对照组相比, MDD患者NA均值更大, PA均值更小, NA惯性和NA变异性更大。 2.与健康对照组相比, MDD患者经历积极事件后表现出心境点亮效应(更大程度的NA减少)。 3.与健康对照组相比, MDD患者NA情绪不稳定性更大。但控制情绪变异性的效应后, 这两个组别的组间差异不显著。	(J. Nelson et al., 2020)
7	1. MDD患者(48) 2. MDD缓解期个体(80)	健康对照 (87)	5×14	PA: relaxed, content, calm, happy, excited, enthusiastic NA: bored, sluggish, sad, frustrated, nervous, angry	1. MDD患者的NA均值和NA变异性最大, 健康对照组最小, 处于缓解期的个体介于两者之间。控制NA均值后, NA变异性的组间差异仍显著。 2. 3个组别NA惯性的组间差异不显著。 3. 对于PA的情绪动力指标而言, 只有PA均值在3个组别的组间差异显著。抑郁症患者的PA均值小于处于缓解期的个体和健康对照组, 而处于缓解期的个体和健康对照组的PA均值没有显著差异。	& English, 2021)
8	具有MDD终身诊断的患者(116), 其中40.5%当前被诊断为MDD	1. 健康对照(65) 2. 双相障碍I型(33) 3. 双相障碍II型(37) 4. 焦虑障碍(36)	4×14	效价: very happy (1) to very sad (7) 唤醒程度: very calm (1) to very anxious (7)	1.与健康对照组相比, 具有MDD终身诊断的患者悲伤、焦虑情绪的均值和焦虑情绪的变异性, 以及悲伤、焦虑情绪的不稳定性更大。 2.经历积极事件后, 具有MDD终身诊断的患者(相比健康对照组)表现出心境点亮效应(更大程度的焦虑情绪减少)。经历消极事件后, 具有MDD终身诊断的患者表现出更大的NA情绪反应性(更大程度的焦虑情绪增加)。 3.进一步将具有MDD终身诊断的患者细分为当下患有MDD的患者、处于缓解期的个体两个组别后, 两个组别的情绪反应性没有显著差异。	(Lamers et al., 2018)
9	MDD患者且共病BPD (20)	MDD患者没有共病BPD (21)	5×7	PA: happy, content, relaxed NA: sad, anxious, angry, empty, lonely, guilty, tense	1.共病BPD和不共病BPD的两组MDD患者在情绪不稳定性, 以及与他人积极互动/与他人消极互动/感知到被拒绝/感知到失败后的总体情绪反应性上没有组间差异。 2.相比于不共病BPD的MDD患者, 共病BPD的MDD患者在经历了独自一人的事件后体验到了更大的情绪反应性(更大程度的总体情绪恶化)。	(Köhling et al., 2016)
10	1. 患MDD的大一学生(23) 2. 缓解期的大一学生(42)	无MDD病史的大一学生(43)	4×14	NA: sad, alone, angry with self, guilty, lonely, hopeless	1. 相比于处于缓解期和无MDD病史的个体, MDD患者对于日常感知到的压力表现出更大的NA情绪反应性(更大程度的NA增加)。 2. MDD患者对人际消极事件表现出更大的NA情绪反应性(更大程度的NA增加), 而处于缓解期和无MDD病史的个体对人际或非人际的消极事件的情绪反应性没有显著差异。	(Sheets & Armey, 2020)
11	MDD患者(30), 治疗后分为: 1.症状缓解组(11) 2.症状没有缓解组(19)	健康对照 (39)	10×6	PA: energetic, enthusiastic, happy, cheerful, talkative, strong, satisfied, self-assured NA: anxious, irritated, restless, tense, guilty, edgy, distractible, agitated	1.相比于健康对照组和缓解期组, 症状未缓解的MDD患者对事件、活动和社交这三种应激源的NA情绪反应性更大(更大程度的NA增加)。 2.缓解期组和健康对照组在对事件和活动应激源的情绪反应性上没有组间差异, 但是缓解期组(相对于健康对照组)仍表现出对社交应激源更大的NA情绪反应性(更大程度的NA增加)。	(van Winkel et al., 2015)
12	MDD或GAD患者(61)	健康对照(58)	9×8	PA: relaxed, content, excited, enthusiastic NA: angry, tired, irritable, anxious, depressed	基于EMA得到的NA和PA的网络密度都在人口学特征和情绪均值、标准差之上显著预测个体的诊断状态。具体而言, 更大的NA情绪网络密度、更小的PA情绪网络密度与MDD/GAD的诊断存在相关。	(Shin et al., 2022)
13	处于复发性MDD缓解期的个体(51)	健康对照(51)	10×5	PA: cheerful, energetic, enthusiastic, satisfied, relaxed, calm NA: upset, irritated, nervous, listless, down, bored	1.处于复发性MDD缓解期的个体(相比于健康对照组)在经历消极日常事件后表现出更大的NA情绪反应性(更大程度的NA增加)。 2.处于复发性MDD缓解期的个体(相比于健康对照组)在经历积极日常事件后表现出心境点亮效应(更大程度的PA增加和更大程度的NA减少)。	(Schricker et al., 2022)
14	1.MDD不共病GAD (38) 2.MDD共病GAD (38)	1.GAD, 且不共病MDD (36) 2.健康对照(33)	8×7	PA: happy, proud, determined NA: sad, anxious, dissatisfied with myself	1.MDD不共病GAD组和MDD共病GAD组的患者(相比于健康对照组)在经历积极事件后都表现出心境点亮效应 (更大程度的PA增加和更大程度的NA减少)。 2.患者基线抑郁症状越严重, 心境点亮效应更强。 3.与GAD相比, MDD对积极事件的情绪反应性改变更具有特异性。	(Khazanov et al., 2019)
15	MDD患者(31)	健康对照 (33)	10×6	PA: happy, relaxed, interested, enjoying myself NA: irritated, down, anxious, tense, ashamed, guilty	1. 相比于健康对照组, MDD患者表现出更大的NA和PA的情绪变异性和不稳定性。 2. MDD患者和健康对照组在日间积极情绪的时间趋势上存在差异, MDD患者每天积极情绪随时间的变化呈现为倒U型, 而健康对照组呈现为正向的线性趋势。	(Crowe et al., 2019)
16	MDD患者(41)	健康对照 (33)	10×3	DA: depressed, sad	相比于健康对照组, MDD患者在经历日常积极事件后表现出心境点亮效应(更大程度的烦躁情绪减少)。	(Panaite et al., 2018)
17	DD患者(38)	BPD患者(67)	6×28	NA: fear (6 items) hostility (6 items) sadness (5 items) 详见(Watson & Clark, 1994)	1. DD患者NA情绪分化水平高于BPD患者。 2. NA情绪分化水平可以负向预测冲动性, 但预测的效应在DD患者和BPD患者两个组别中没有显著差异。	(Tomko et al., 2015)
18	有MDD既往诊断史, 且目前轻度抑郁的患者(129)	1. 健康对照(207) 2. 精神病性障碍患者(263)	10× (5/6)	PA: cheerful, content NA: insecure, down, suspicious	1.相比于精神病性障碍组和健康对照组, 抑郁症患者的情绪状态网络的节点间的联系最为紧密。 2.相比于精神病性障碍组, 抑郁症患者的网络结构表现出更多的积极和消极心理状态之间的特异性联系。	(Wigman et al., 2015)

序号	文献	依从性	信度	效度
1	Heininga et al., 2019	问卷填写依从率达到89%。	PA的个体内Cronbach’s α = 0.03, 个体间Cronbach’s α = 0.99	效标效度：文章中报告：与健康对照组相比, 伴有快感缺失的MDD患者PA均值更低。
2	Schoevers et al., 2021	发给所有被试的所有问卷中, 仅8.72%缺失。93%的参与者填写率超过80%。	未报告	1) 效标效度：文章中报告：当前患有MDD/AD患者NA均值最高, 其次是缓解期个体, 最后是健康对照组。PA则相反。该文献的附录提供了各情绪条目在3个组别中的均值。 2) 结构效度：附录中提供了各情绪条目和PA、NA总分之间的相关系数。
3	Minaeva et al., 2021	621个被试中, 有610个被试完成了EMA测量。	1) PA的个体内omega为0.79; 个体间omega为0.95。 2) NA的个体内omega为0.68; 个体间omega为0.91。	1) 效标效度：正文表格1表明：MDD患者的NA中位数最大, 其次是缓解期个体, 最后是健康对照组。PA均值则相反。 2) 结构效度：该研究选择过往研究在PA、NA潜因子上具有最高因子负荷和个体内变异性的条目。
4	Pe et al., 2015	未报告	未报告	效标效度：文章中报告：MDD患者的NA网络密度大于健康对照组。
5	Thompson, Liu, et al., 2021	平均问卷完成率为74.8%, 标准差18.3%, 范围在20%到99%。	通过混合模型得到PA的Cronbach’s α为0.65, NA的Cronbach’s α为0.74。PA和NA具有足够的个体内变异性, PA的ICC为0.42, NA的ICC为0.43。	效标效度： 1) 文章中报告了健康对照组、处于抑郁症缓解期组和MDD患者组在NA和PA均值存在组间差异。 2) 正文表1展示了NA均值和PA均值与抑郁症状之间的相关。NA均值与MASQ抑郁量表之间的斯皮尔曼相关系数为0.45, 与CES-D抑郁量表之间的斯皮尔曼相关系数为0.54。PA均值与MASQ抑郁量表之间的斯皮尔曼相关系数为−0.52, 与CES-D抑郁量表之间的斯皮尔曼相关系数为−0.47。
6	J. Nelson et al., 2020	抑郁症组EMA问卷完成率为90%, 健康对照组完成率为87%。	ICC的结果表明：对于PA, 71%的总方差是个体间方差, 29%的总方差是个体内方差。对于NA, 66%的总方差是个体间方差, 34%的总方差是个体内方差。	结构效度：探索性因素分析的结果表明：情绪问卷是双因子结构, PA和NA分别是两个因子。
7	Thompson, Bailen, et al., 2021
8	Lamers et al., 2018	平均每个被试完成了56次问卷测量中的44次, 平均完成率为78.5%。	未报告	1) 内容效度：条目的选择参考过去大量EMA研究和咨询了睡眠、头痛和健康等相关领域的专家。 2) 效标效度：文章中报告：与健康对照组相比, 具有MDD终身诊断的患者悲伤、焦虑情绪的均值更大。
9	Köhling et al., 2016	所有参与者平均问卷完成率为94.8%。	1) PA的个体间信度R_KF为0.98, 个体内信度R_C为0.81。 2) NA的个体间信度R_KF为0.99, 个体内信度R_C为0.80。	依据情绪环状模型和过去相关研究选择情绪条目。
10	Sheets & Armey, 2020	平均问卷完成率为63%。	NA的个体间信度为0.97, 个体内信度为0.78。	1) 从过去相关研究的量表中选择问卷条目。 2) 效标效度：文章中报告了健康对照组、处于抑郁症缓解期组和MDD患者组在NA均值存在组间差异。
11	van Winkel et al., 2015	基线阶段的EMA平均问卷完成率为85%, 追踪阶段的EMA平均问卷完成率为81%。	PA的Cronbach’s α为0.97, NA的Cronbach’s α为0.95。基线数据的主成分分析得到的两个特征值大于1的因子可以分别解释81%的情绪个体间方差和46%的情绪个体内方差。	结构效度：基线数据的主成分分析得到了两个特征值大于1的因子, 分别为积极情绪和消极情绪潜因子。
12	Shin et al., 2022	EMA数据集的平均问卷完成率为80%, 平均每人填写57次问卷, 标准差为13。	未报告	1) 依据情绪环状模型选择涵盖不同效价和唤醒程度的情绪条目。 2) 效标效度： EMA得到的NA和PA的网络密度都在人口学特征和情绪均值、标准差之上显著预测个体的诊断状态。
13	Schricker et al., 2022	平均问卷完成率为91.1%, 标准差为9.4, 范围为48%到100%。	1) PA的个体内信度为0.60; 个体间信度为0.99。 2) NA的个体内信度为0.69; 个体间信度为0.98。 3) 所有EMA条目的ICC在0.44到0.66之间。	1) 依据PANAS量表和从过去相关研究选择情绪条目。 2) 效标效度：文章中报告了EMA变量的组间差异。
14	Khazanov et al., 2019	平均问卷完成率为72%, 标准差为12.7, 范围为41%到98%。	1) 验证性因子模型得到的各PA条目的个体内信度ω在0.63到0.72之间。 2) 验证性因子模型得到的各NA条目的个体内信度ω在0.75到0.77之间。	1) 依据PANAS量表选择情绪条目。 2) 结构效度： EMA测得瞬时PA和PANAS测得的特质PA之间的相关性在0.60到0.63之间。EMA测得瞬时NA和PANAS测得的特质NA之间的相关性在0.60到0.61之间。
15	Crowe et al., 2019	共收集到了2548份问卷, MDD患者平均每人填写33.1份有效问卷, 健康对照组平均每人填写36.5份有效问卷。	1) 多水平探索性因素分析得到的PA的个体间信度为0.82, 个体内信度为0.46。 2) 多水平探索性因素分析得到的NA的个体间信度为0.84, 个体内信度为0.50。 3) PA的ICC为0.62, NA的ICC为0.75。	结构效度：多水平探索性因素分析的结果表明：个体内和个体间层级都存在积极情绪和消极情绪双因子结构。
16	Panaite et al., 2018	未报告	DA的ICC为0.83。	1) 参考过去研究选择条目。 2) 效标效度：文章中报告：相比于健康对照组, MDD患者EMA测得的烦躁情绪均值更大。
17	Tomko et al., 2015	平均问卷完成率为86%, 平均每个参与者填写了147.1次问卷。	MDD患者组NA的ICC为0.60, BPD患者组NA的ICC为0.66。	选择PANAS量表中的条目作为EMA施测条目。
18	Wigman et al., 2015	未报告	未报告	效标效度：正文中表2报告了MDD组、精神病性障碍组和健康对照组在5种EMA测得的心理状态之间的组间差异。
报告比率		15/18	13/18	18/18