ISSN 0439-755X
CN 11-1911/B
主办：中国心理学会
　　　中国科学院心理研究所
出版：科学出版社

心理学报 ›› 1998, Vol. 30 ›› Issue (3): 326-331.

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一日龄小鸡的不同记忆阶段中Jun样蛋白在脑内HV和LPO的表达

胡家芬;管林初;匡培梓;姜树军;匡培根   

  1. 中国科学院心理研究所脑－行为研究中心,中国人民解放军总医院神经介质实验室
  • 发布日期:1998-09-25 出版日期:1998-09-25
  • 通讯作者: 胡家芬

EXPRESSION OF JUN-LIKE PROTEIN IN HV AND LPO OF ONE-DAY-OLD CHICKS'BRAINS DURING DIFFERENT MEMORY PHASES

Hu Jiafen Guan Linchu Kuang Peizi(Brain-Behavior Research Center,Institute of Psychology,Chinese Academy of Sciences,Beijing 1000l2,China) Jiang Shujun KuangPeigen (Neurotransmitter Research Laboratory ,C   

  • Online:1998-09-25 Published:1998-09-25

摘要： 以一日龄小鸡为研究对象，采用一次性被动回避反应试验和免疫组织化学相结合的方法，选用六个时间点（１０、３０、７０分钟及４、８和２４小时）对Ｊｕｎ样蛋白在小鸡左右侧脑内ＨＶ和ＬＰＯ两部位的表达进行了探讨。结果表明Ｊｕｎ样蛋白在小鸡学习过程中特异地表达。这种表达存在部位上的差异，即在ＬＰＯ区的表达明显高于ＨＶ区。由于ｃ－ｊｕｎ基因在不同时段表达水平的变化与小鸡记忆痕迹的迁移有着相似的趋势，说明Ｊｕｎ样蛋白可能参与了记忆的巩嵐毯椭婀獭

关键词: 一日龄小鸡, 记忆, Jun样蛋白, HV, LPO

Abstract: One-day-old chicks were trained with 100%concentration of a taste aversantchemical,methyl anthranilate(MeA),and tested for memory retention at 6 differenttime points ( 10, 30 and 70minutes; 4, 8 and 24hours)after training. The brainsections were examined with immunohistochemistry method.The number of cellswhich expressed Jun-like protein was counted under the micmscope and analysed byANOVA statistical system.The results showed that Jun-like protein expression wasspecifically activated by the leaning course in one-day-old chicks. There existeddifferences among different areas in the brain,that is to say, more Jun-like protein in LPO than that in HV on the whole.Because Jun-like protein expression had similartendency with the memory trace in chicks,it could be deduced that c-jun gene mightplay an important role in the consolidation and retention of the chicks'memory.

Key words: one-day-chicks, memory, Jun-like protein, HV, LP0