Feedback-related negativity and addiction

doi:10.3724/SP.J.1042.2020.00959

Abstract

Abstract:

Feedback-related negativity (FRN) refers to the electroencephalogram component induced by feedback processing which reflects the individual's sensitivity to reward. Addiction can be broadly classified into substance addiction and behavior addiction. Both types of addicted individuals show pathological patterns in feedback processing. Comparing with the ordinary feedback (such as money), the FRN amplitude induced by feedback of addiction substance significantly increased in individuals with substance addiction. In the control study with non-addicted subjects, substance addicts also showed abnormal patterns relating to addiction when processing monetary feedback stimuli. Similar FRN irregularities were also observed in individuals with behavioral addiction. However, the classification of addiction disorders in most previous studies is not specific enough, and the characteristics of different subtypes of addiction disorders should be further taken into consideration in future studies. Moreover, addicted individuals are often accompanied by other mental disorders (such as depression, anxiety). Further studies should distinguish the influences of comorbid factors and reveal the unique reward processing mechanisms underlying addiction.

Key words: feedback-related negativity, substance addiction, behavioral addiction, reinforcement learning, reward mechanism

CLC Number:

B845

CHEN Lele, HUANG Rong, JIA Shiwei. Feedback-related negativity and addiction[J]. Advances in Psychological Science, 2020, 28(6): 959-968.

Figures/Tables 2

References 70

[1]	李丹阳, 李鹏, 李红 . (2018). 反馈负波及其近10年理论解释. 心理科学进展, 26(9), 1642-1650.
[2]	李鹏, 李红 . (2008). 反馈负波及其理论解释. 心理科学进展, 16(5), 705-711.
[3]	杨玲, 王斌强, 耿银凤, 姚东伟, 曹华, 张建勋, 许琼英 . (2019). 虚拟和真实金钱奖赏幅度对海洛因戒断者风险决策的影响. 心理学报, 51(4), 507-516.
[4]	Ahlskog, J. E . (2011). Pathological behaviors provoked by dopamine agonist therapy of Parkinson's disease. Physiology & Behavior, 104(1), 168-172.
[5]	Ahmed, S. H . (2005). Imbalance between drug and non-drug reward availability: A major risk factor for addiction. European Journal of Pharmacology, 526(1-3), 9-20. doi: 10.1016/j.ejphar.2005.09.036 URL
[6]	American Psychiatric Association. DSM-5 Task Force. (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5™. Arlington, VA, US.
[7]	Baker, T. B., Piper, M. E., McCarthy, D. E., Majeskie, M. R., & Fiore, M. C . (2004). Addiction motivation reformulated: An affective processing model of negative reinforcement. Psychological Review, 111(1), 33-51. doi: 10.1037/0033-295X.111.1.33 URL
[8]	Baker, T. E., Lesperance, P., Tucholka, A., Potvin, S., Larcher, K., Zhang, Y., ... Conrod, P . (2017). Reversing the atypical valuation of drug and nondrug rewards in smokers using multimodal neuroimaging. Biological Psychiatry, 82(11), 819-827. doi: 10.1016/j.biopsych.2017.01.015 URL
[9]	Baker, T. E., Stockwell, T., Barnes, G., & Holroyd, C. B . (2011). Individual differences in substance dependence: At the intersection of brain, behaviour and cognition. Addiction Biology, 16(3), 458-466. doi: 10.1111/j.1369-1600.2010.00243.x URL
[10]	Baker, T. E., Stockwell, T., Barnes, G., Haesevoets, R., & Holroyd, C. B . (2016). Reward sensitivity of ACC as an intermediate phenotype between DRD4-521T and substance misuse. Journal of Cognitive Neuroscience, 28(3), 460-471. doi: 10.1162/jocn_a_00905 URL
[11]	Baker, T. E., Wood, J. M. A., & Holroyd, C. B . (2016). Atypical valuation of monetary and cigarette rewards in substance dependent smokers. Clinical Neurophysiology, 127(2), 1358-1365. doi: 10.1016/j.clinph.2015.11.002 URL
[12]	Baler, R. D., & Volkow, N. D . (2006). Drug addiction: The neurobiology of disrupted self-control. Trends in Molecular Medicine, 12(12), 559-566. doi: 10.1016/j.molmed.2006.10.005 URL
[13]	Bjork, J. M., Momenan, R., Smith, A. R., & Hommer, D. W . (2008). Reduced posterior mesofrontal cortex activation by risky rewards in substance-dependent patients. Drug and Alcohol Dependence, 95(1-2), 115-128. doi: 10.1016/j.drugalcdep.2007.12.014 URL
[14]	Blum, K., Braverman, E. R., Holder, J. M., Lubar, J. F., Monastra, V. J., Miller, D., ... Comings, D. E . (2000). The reward deficiency syndrome: A biogenetic model for the diagnosis and treatment of impulsive, addictive and compulsive behaviors. Journal of Psychoactive Drugs, 32(suppl1-4), 1-112.
[15]	Bodkyn, C. N., & Holroyd, C. B . (2019). Neural mechanisms of affective instability and cognitive control in substance use. International Journal of Psychophysiology, 146, 1-19. doi: 10.1016/j.ijpsycho.2019.08.003 URL
[16]	Bolla, K., Ernst, M., Kiehl, K., Mouratidis, M., Eldreth, D., Contoreggi, C., … London, E . (2004). Prefrontal cortical dysfunction in abstinent cocaine abusers. Journal of Neuropsychiatry and Clinical Neurosciences, 16(4), 456-464. doi: 10.1176/jnp.16.4.456 URL
[17]	Carbonell, X . (2017). From pong to pokemon go, catching the essence of the internet gaming disorder diagnosis. Journal of Behavioral Addictions, 6(2), 124-127. doi: 10.1556/2006.6.2017.010 URL
[18]	Cockburn, J., & Holroyd, C. B . (2018). Feedback information and the reward positivity. International Journal of Psychophysiology, 132, 243-251. doi: 10.1016/j.ijpsycho.2017.11.017 URL
[19]	Euser, A. S., Greaves-Lord, K., Crowley, M. J., Evans, B. E., Huizink, A. C., & Franken, I. H. A . (2013). Blunted feedback processing during risky decision making in adolescents with a parental history of substance use disorders. Development and Psychopathology, 25(4pt1), 1119-1136. doi: 10.1017/S0954579413000412 URL
[20]	Euser, A. S., van Meel, C. S., Snelleman, M., & Franken, I. H. A . (2011). Acute effects of alcohol on feedback processing and outcome evaluation during risky decision-making: An ERP study. Psychopharmacology, 217(1), 111. doi: 10.1007/s00213-011-2264-x URL
[21]	Fein, G., & Chang, M . (2008). Smaller feedback ERN amplitudes during the BART are associated with a greater family history density of alcohol problems in treatment- naive alcoholics. Drug and Alcohol Dependence, 92(1-3), 141-148. doi: 10.1016/j.drugalcdep.2007.07.017 URL
[22]	Franken, I. H. A., van den Berg, I., & van Strien, J. W . (2010). Individual differences in alcohol drinking frequency are associated with electrophysiological responses to unexpected nonrewards. Alcoholism: Clinical and Experimental Research, 34(4), 702-707. doi: 10.1111/acer.2010.34.issue-4 URL
[23]	Gehring, W. J., & Willoughby, A. R . (2002). The medial frontal cortex and the rapid processing of monetary gains and losses. Science, 295(5563), 2279-2282.
[24]	Goldstein, R. Z., Parvaz, M. A., Maloney, T., Alia-Klein, N., Woicik, P. A., Telang, F., ... Volkow, N. D . (2008). Compromised sensitivity to monetary reward in current cocaine users: An ERP study. Psychophysiology, 45(5), 705-713.
[25]	Goldstein, R. Z., Tomasi, D., Alia-Klein, N., Cottone, L. A., Zhang, L., Telang, F., & Volkow, N. D . (2007). Subjective sensitivity to monetary gradients is associated with frontolimbic activation to reward in cocaine abusers. Drug and Alcohol Dependence, 87(2-3), 233-240.
[26]	Gu, R., Jiang, Y., Kiser, S., Black, C. L., Broster, L. S., Luo, Y. J., & Kelly, T. H . (2017). Impulsive personality dimensions are associated with altered behavioral performance and neural responses in the monetary incentive delay task. Neuropsychologia, 103, 59-68.
[27]	Haber, S. N., & Knutson, B . (2010). The reward circuit: Linking primate anatomy and human imaging. Neuropsychopharmacology, 35(1), 4-26.
[28]	Hajcak, G., Moser, J. S., Holroyd, C. B., & Simons, R. F . (2006). The feedback-related negativity reflects the binary evaluation of good versus bad outcomes. Biological Psychology, 71(2), 148-154.
[29]	He, W., Qi, A., Wang, Q., Wu, H., Zhang, Z., Gu, R., & Luo, W . (2017). Abnormal reward and punishment sensitivity associated with Internet addicts. Computers in Human Behavior, 75, 678-683.
[30]	Hewig, J., Kretschmer, N., Trippe, R. H., Hecht, H., Coles, M. G. H., Holroyd, C. B., & Miltner, W. H. R . (2010). Hypersensitivity to reward in problem gamblers. Biological Psychiatry, 67(8), 781-783.
[31]	Hixson, H., Burkhouse, K. L., Gorka, S. M., & Klumpp, H . (2019). A preliminary examination of the relation between neural sensitivity to reward and history of alcohol use disorder among adults with internalizing psychopathologies. Neuroscience Letters, 690, 17-22.
[32]	Holroyd, C. B., & Coles, M. G. H . (2002). The neural basis of human error processing: Reinforcement learning, dopamine, and the error-related negativity. Psychological Review, 109(4), 679-709.
[33]	Holroyd, C. B., Pakzad-Vaezi, K. L., & Krigolson, O. E . (2008). The feedback correct-related positivity: Sensitivity of the event-related brain potential to unexpected positive feedback. Psychophysiology, 45(5), 688-697.
[34]	Howse, A. D., Hassall, C. D., Williams, C. C., Hajcak, G., & Krigolson, O. E . (2018). Alcohol hangover impacts learning and reward processing within the medial-frontal cortex. Psychophysiology, 55(8), e13081.
[35]	Ikemoto, S., & Bonci, A . (2014). Neurocircuitry of drug reward. Neuropharmacology, 76, 329-341. doi: 10.1016/j.neuropharm.2013.04.031 URL
[36]	Jiang, D., Zhang, D., Chen, Y., He, Z., Gao, Q., Gu, R., & Xu, P . (2018). Trait anxiety and probabilistic learning: Behavioral and electrophysiological findings. Biological Psychology, 132, 17-26.
[37]	Kamarajan, C., Rangaswamy, M., Tang, Y., Chorlian, D. B., Pandey, A. K., Roopesh, B. N., ... Porjesz, B . (2010). Dysfunctional reward processing in male alcoholics: An ERP study during a gambling task. Journal of Psychiatric Research, 44(9), 576-590.
[38]	Koob, G. F . (2013). Negative reinforcement in drug addiction: The darkness within. Current Opinion in Neurobiology, 23(4), 559-563.
[39]	Koob, G. F., & Le Moal, M . (2005). Plasticity of reward neurocircuitry and the 'dark side' of drug addiction. Nature Neuroscience, 8(11), 1442-1444.
[40]	Krigolson, O. E . (2018). Event-related brain potentials and the study of reward processing: Methodological considerations. International Journal of Psychophysiology, 132, 175-183.
[41]	Kuss, D. J., & Lopez-Fernandez, O . (2016). Internet addiction and problematic internet use: A systematic review of clinical research. World Journal of Psychiatry, 6(1), 143-176.
[42]	Leshner, A. I . (1997). Addiction Is a Brain Disease, and It Matters. Science, 278(5335), 45-47.
[43]	Li, P., Peng, W., Li, H., & Holroyd, C. B . (2018). Electrophysiological measures reveal the role of anterior cingulate cortex in learning from unreliable feedback. Cognitive, Affective, & Behavioral Neuroscience, 18(5), 949-963.
[44]	Li, Q., Wang, Y., Yang, Z., Dai, W., Zheng, Y., Sun, Y., & Liu, X . (2019). Dysfunctional cognitive control and reward processing in adolescents with Internet gaming disorder. Psychophysiology, e13469.
[45]	Lole, L., Gonsalvez, C. J., & Barry, R. J . (2015). Reward and punishment hyposensitivity in problem gamblers: A study of event-related potentials using a principal components analysis. Clinical Neurophysiology, 126(7), 1295-1309. doi: 10.1016/j.clinph.2014.10.011 URL
[46]	Miltner, W. H. R., Braun, C. H., & Coles, M. G. H . (1997). Event-related brain potentials following incorrect feedback in a time-estimation task: Evidence for a "generic" neural system for error detection. Journal of Cognitive Neuroscience, 9(6), 788-798. doi: 10.1162/jocn.1997.9.6.788 URL
[47]	Morie, K. P., de Sanctis, P., Garavan, H., & Foxe, J. J . (2016). Regulating task-monitoring systems in response to variable reward contingencies and outcomes in cocaine addicts. Psychopharmacology, 233(6), 1105-1118.
[48]	Morie, K. P., Wu, J., Landi, N., Potenza, M. N., Mayes, L. C., & Crowley, M. J . (2018). Feedback processing in adolescents with prenatal cocaine exposure: An electrophysiological investigation. Developmental Neuropsychology, 43(3), 183-197. doi: 10.1080/87565641.2018.1439945 URL
[49]	Muñoz, M. Á., Anllo-Vento, L., del Carmen Fernández, M., Montoya, P., & Vila, J . (2012). Modulation of the outcome-related negativity associated with nicotine abstinence. Experimental and Clinical Psychopharmacology, 20(2), 151. doi: 10.1037/a0025991 URL
[50]	Nelson, L. D., Patrick, C. J., Collins, P., Lang, A. R., & Bernat, E. M . (2011). Alcohol impairs brain reactivity to explicit loss feedback. Psychopharmacology, 218(2), 419-428.
[51]	Nestor, L., Hester, R., & Garavan, H . (2010). Increased ventral striatal BOLD activity during non-drug reward anticipation in cannabis users. Neuroimage, 49(1), 1133-1143. doi: 10.1016/j.neuroimage.2009.07.022 URL
[52]	Oberg, S. A. K., Christie, G. J., & Tata, M. S . (2011). Problem gamblers exhibit reward hypersensitivity in medial frontal cortex during gambling. Neuropsychologia, 49(13), 3768-3775. doi: 10.1016/j.neuropsychologia.2011.09.037 URL
[53]	Parvaz, M. A., Konova, A. B., Proudfit, G. H., Dunning, J. P., Malaker, P., Moeller, S. J., ... Goldstein, R. Z . (2015). Impaired neural response to negative prediction errors in cocaine addiction. Journal of Neuroscience, 35(5), 1872-1879. doi: 10.1523/JNEUROSCI.2777-14.2015 URL
[54]	Peoples, L. L . (2002). Neuroscience: Will, anterior cingulate cortex, and addiction. Science, 296(5573), 1623-1624.
[55]	Petry, N. M . (2006). Should the scope of addictive behaviors be broadened to include pathological gambling? Addiction, 101( Suppl 1), 152-160. doi: 10.1111/add.2006.101.issue-s1 URL
[56]	Potenza, M. N . (2006). Should addictive disorders include non-substance-related conditions? Addiction, 101(Suppl. 1), 142-151.
[57]	Potts, G. F., Bloom, E. L., Evans, D. E., & Drobes, D. J . (2014). Neural reward and punishment sensitivity in cigarette smokers. Drug and Alcohol Dependence, 144, 245-253. doi: 10.1016/j.drugalcdep.2014.09.773 URL
[58]	Proudfit, G. H . (2015). The reward positivity: From basic research on reward to a biomarker for depression. Psychophysiology, 52(4), 449-459.
[59]	Quandt, T . (2017). Stepping back to advance: Why IGD needs an intensified debate instead of a consensus. Journal of Behavioral Addictions, 6(2), 121-123.
[60]	Redish, A. D., Jensen, S., & Johnson, A . (2008). A unified framework for addiction: Vulnerabilities in the decision process. Behavioral & Brain Sciences, 31(4), 415-437.
[61]	Robinson, T. E., & Berridge, K. C . (1993). The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Research Reviews, 18(3), 247-291.
[62]	Soder, H. E., Webber, T. A., Bornovalova, M. A., Park, J. Y., & Potts, G. F . (2019). A test of dopamine hyper-and hyposensitivity in alcohol use. Addictive Behaviors, 90, 395-401.
[63]	Torres, A., Catena, A., Cándido, A., Maldonado, A., Megías, A., & Perales, J. C . (2013). Cocaine dependent individuals and gamblers present different associative learning anomalies in feedback-driven decision making: A behavioral and ERP study. Frontiers in Psychology, 4, 122.
[64]	Ulrich, N., & Hewig, J . (2018). Electrophysiological correlates of near outcome and outcome sequence processing in problem gamblers and controls. International Journal of Psychophysiology, 132, 379-392.
[65]	van Rooij, A. J., Ferguson, C. J., Colder, C. M., Kardefelt- Winther, D., Shi, J., Aarseth, E., ... Przybylski, A. K . (2018). A weak scientific basis for gaming disorder: Let us err on the side of caution. Journal of Behavior Addiction, 7(1), 1-9.
[66]	Voon, V., Gao, J., Brezing, C., Symmonds, M., Ekanayake, V., Fernandez, H., ... Hallett, M . (2011). Dopamine agonists and risk: Impulse control disorders in Parkinson's disease. Brain, 134(5), 1438-1446.
[67]	Walsh, J. J., Colino, F. L., Krigolson, O. E., Luehr, S., Gurd, B. J., & Tschakovsky, M. E . (2019). High-intensity interval exercise impairs neuroelectric indices of reinforcement-learning. Physiology & Behavior, 198, 18-26.
[68]	Wei, S., Zheng, Y., Li, Q., Dai, W., Sun, J., Wu, H., & Liu, X . (2018). Enhanced neural responses to monetary rewards in methamphetamine use disordered individuals compared to healthy controls. Physiology & Behavior, 195, 118-127.
[69]	Yau, Y. H. C., Potenza, M. N., Mayes, L. C., & Crowley, M. J . (2015). Blunted feedback processing during risk-taking in adolescents with features of problematic Internet use. Addictive Behaviors, 45, 156-163.
[70]	Yeung, N., & Sanfey, A. G . (2004). Independent coding of reward magnitude and valence in the human brain. Journal of Neuroscience, 24(28), 6258-6264. doi: 10.1523/JNEUROSCI.4537-03.2004 URL

成瘾研究	成瘾物质/行为	程度	N	诊断标准/工具	实验任务	FRN
物质成瘾
Baker et al., 2011	Pol.	亚临床	18	ASSIST	赌博*	普通奖赏物 ↓
Baker et al., 2016	Pol.	亚临床	195	ASSIST	赌博	普通奖赏物 ↓
Baker, Wood, & Holroyd, 2016	Pol.	亚临床	12	ASSIST	赌博	成瘾物质 ↑
Baker et al., 2017	烟草	亚临床	20	FTND	赌博	成瘾物质 ↑
Fein et al., 2008	酒精	临床	22	DSM-Ⅳ	BART	普通奖赏物 ↓
Franken et al., 2010	酒精	正常	47	QFV-I	RPT	普通奖赏物 ↑
Hixson et al., 2019	酒精	临床	15	DSM-Ⅳ	GRT	普通奖赏物 ↑
Kamarajan et al., 2010	酒精	临床	40	DSM-Ⅳ	赌博	普通奖赏物 ↓
Morie et al., 2016	可卡因	临床	23	DSM-Ⅳ	快速反应任务	普通奖赏物 ↓
Muñoz et al., 2012	烟草	亚临床	32	FTND	预测任务	成瘾物质 ↑
Parvaz et al., 2015	可卡因	临床	50	临床访谈	门任务	普通奖赏物 ↓
Potts et al., 2014	烟草	亚临床	22	DSM-Ⅳ	RPT	普通奖赏物 ↑
Soder et al., 2019	酒精	正常	85	DDQ-R	RPT, BART	普通奖赏物 ↓
Wei et al., 2018	甲基苯丙胺	临床	21	DSM-Ⅴ	赌博	普通奖赏物 ↑
行为成瘾
Hewig et al., 2010	赌博	临床	20	DSM-Ⅳ	真实赌博	普通奖赏物 ↑
He et al., 2017	网络	亚临床	16	临床访谈	赌博	普通奖赏物 ↓
Lole et al., 2015	赌博	亚临床	16	PGSI	赌博	普通奖赏物 ↓
Li et al., 2019	网络	临床	34	DSM-Ⅴ	赌博	普通奖赏物 ↓
Oberg et al., 2011	赌博	亚临床	15	CPGI	IGT	普通奖赏物 ↑
Torres et al., 2013	赌博	临床	21	DSM-Ⅳ	反转学习	普通奖赏物 ↓
Ulrich et al., 2018	赌博	亚临床	20	DSM-Ⅳ	赌博	普通奖赏物 ↓
Yau et al., 2015	网络	亚临床	39	临床访谈	BART	普通奖赏物 ↓

成瘾研究	成瘾物质/行为	程度	N	诊断标准/工具	实验任务	FRN
物质成瘾
Baker et al., 2011	Pol.	亚临床	18	ASSIST	赌博*	普通奖赏物 ↓
Baker et al., 2016	Pol.	亚临床	195	ASSIST	赌博	普通奖赏物 ↓
Baker, Wood, & Holroyd, 2016	Pol.	亚临床	12	ASSIST	赌博	成瘾物质 ↑
Baker et al., 2017	烟草	亚临床	20	FTND	赌博	成瘾物质 ↑
Fein et al., 2008	酒精	临床	22	DSM-Ⅳ	BART	普通奖赏物 ↓
Franken et al., 2010	酒精	正常	47	QFV-I	RPT	普通奖赏物 ↑
Hixson et al., 2019	酒精	临床	15	DSM-Ⅳ	GRT	普通奖赏物 ↑
Kamarajan et al., 2010	酒精	临床	40	DSM-Ⅳ	赌博	普通奖赏物 ↓
Morie et al., 2016	可卡因	临床	23	DSM-Ⅳ	快速反应任务	普通奖赏物 ↓
Muñoz et al., 2012	烟草	亚临床	32	FTND	预测任务	成瘾物质 ↑
Parvaz et al., 2015	可卡因	临床	50	临床访谈	门任务	普通奖赏物 ↓
Potts et al., 2014	烟草	亚临床	22	DSM-Ⅳ	RPT	普通奖赏物 ↑
Soder et al., 2019	酒精	正常	85	DDQ-R	RPT, BART	普通奖赏物 ↓
Wei et al., 2018	甲基苯丙胺	临床	21	DSM-Ⅴ	赌博	普通奖赏物 ↑
行为成瘾
Hewig et al., 2010	赌博	临床	20	DSM-Ⅳ	真实赌博	普通奖赏物 ↑
He et al., 2017	网络	亚临床	16	临床访谈	赌博	普通奖赏物 ↓
Lole et al., 2015	赌博	亚临床	16	PGSI	赌博	普通奖赏物 ↓
Li et al., 2019	网络	临床	34	DSM-Ⅴ	赌博	普通奖赏物 ↓
Oberg et al., 2011	赌博	亚临床	15	CPGI	IGT	普通奖赏物 ↑
Torres et al., 2013	赌博	临床	21	DSM-Ⅳ	反转学习	普通奖赏物 ↓
Ulrich et al., 2018	赌博	亚临床	20	DSM-Ⅳ	赌博	普通奖赏物 ↓
Yau et al., 2015	网络	亚临床	39	临床访谈	BART	普通奖赏物 ↓