Abstract:  The dangers of methamphetamine use become increasingly prominent, and has received widely public attention. Numerous evidence from behavioral and neuroimaging studies has consistently shown that chronic methamphetamine consumption can cause a deficit of inhibitory function, particularly in the context of drug-related cues, deriving from dysfunction of the brain regions associated with inhibition, including prefrontal cortex etc. These pathological changes adversely affect cognitive performance and daily function. At present, It has been shown that inhibitory control dysfunction induced by methamphetamine use can be recovered to some degree following abstinence. Therefore, the intervention strategies that devote to improve the inhibitory control of methamphetamine users become very important. Future research in this field should address the specificity of inhibitory control associated with substance use, and consider the patterns of multiple drug abuse and the difference of exercise intervention strategies.

Key words: methamphetamine users, inhibitory control, rehabilitation, intervention