Abstract: With the development of psychological therapy, case formulation as an important part of the psychotherapy has gradually become the clinical focus. The presented case formulation, which is based on certain psychotherapy theory, makes clinical assumption about the aetiological and maintaining factors, and provides blueprint to the establishment of treatment plans. According to the clinical researches of western countries, case formulation is effective in promoting the therapist and client’s understandings toward the symptom and improving the therapeutic effect. The case formulation is based on the cognitive and behavior therapy, and then used to illustrate the application of case formulation in clinical treatment of anxiety and depression.

Key words: case formulation, cognitive behavior therapy, anxiety, depression