ISSN 1671-3710
CN 11-4766/R
主办：中国科学院心理研究所
出版：科学出版社

心理科学进展 ›› 2018, Vol. 26 ›› Issue (3): 488-495.doi: 10.3724/SP.J.1042.2018.00488

• 研究前沿 • 上一篇    下一篇

 阿尔茨海默病的早期阶段：主观认知障碍？

 张馨月; 余 林   

  1.  (西南大学心理学部心理健康与社会适应实验室; 西南大学心理健康教育研究中心, 重庆 400715)
  • 收稿日期:2017-04-21 出版日期:2018-03-15 发布日期:2018-01-31
  • 通讯作者: 余林, E-mail: yulin@swu.edu.cn E-mail:E-mail: yulin@swu.edu.cn
  • 基金资助:
    重庆市人文社会科学重点研究基地重点项目资助，项目号：16SKB026

 The early stages of Alzheimer’s disease: Subjective cognitive impairment?

 ZHANG Xinyue; YU Lin   

  1.  (Laboratory for Mental Health and Social Adaptation, School of Psychology, Southwest University; Center for Mental Health Education, Southwest University, Chongqing 400715, China)
  • Received:2017-04-21 Online:2018-03-15 Published:2018-01-31
  • Contact: YU Lin, E-mail: yulin@swu.edu.cn E-mail:E-mail: yulin@swu.edu.cn
  • Supported by:
     

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摘要：  主观认知障碍(subjective cognitive impairment, SCI)是指个体有认知障碍主诉, 但不存在认知障碍或病理方面的客观证据, 近年来成为阿尔茨海默病(AD)研究领域关注的热点问题, 不仅是因为其症状本身较为常见, 而且研究人员发现SCI的患者相比无SCI患AD的概率更大, 极有可能是AD及轻度认知障碍(Mild cognitive impairment, MCI)的更早阶段。但目前学界就该症状的预测效果存在极大分歧。本文对主观认知障碍的研究状况进行了系统梳理, 主要包括其概念与测量, 脑变化与生物标志物, 与MCI和AD的关系及对未来研究方向的展望。

关键词: 主观认知障碍, 阿尔茨海默病, 预测

Abstract:  Subjective cognitive impairment (SCI) is referred to as a cognitive impairment complaints with no pathological aspects of objective evidence. In recent years it has become a hot topic of concern in the field of dementia research since researchers have found that SCI patients are more likely to suffer from AD, thus it is likely to be an earlier stage of AD and MCI. There are however, great differences in the prediction effect of SCI. This paper systematically reviews recent researches status of subjective cognitive impairment, including the concepts and measurement of subjective cognitive impairment, brain changes and bio-markers, and the relationship between SCI and AD and prospects for the future research.

Key words: subjective cognitive impairment, Alzheimer's disease, prediction

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