ISSN 1671-3710
CN 11-4766/R
主办:中国科学院心理研究所
出版:科学出版社

心理科学进展 ›› 2013, Vol. 21 ›› Issue (12): 2164-2173.doi: 10.3724/SP.J.1042.2013.02164

• 研究前沿 • 上一篇    下一篇

社会互动对青春期啮齿类动物药物成瘾易感性的影响

赵钰丹;李新旺;田琳;杨钒   

  1. (首都师范大学心理系, 北京 100037)
  • 收稿日期:2013-05-06 出版日期:2013-12-15 发布日期:2013-12-15
  • 通讯作者: 李新旺

Social Interaction Influence on Adolescent Rodents’ Susceptibility to Drug Addiction

ZHAO Yudan;LI Xinwang;TIAN Lin;YANG Fan   

  1. (Department of Psychology, Capital Normal University, Beijing 100037, China)
  • Received:2013-05-06 Online:2013-12-15 Published:2013-12-15
  • Contact: LI Xinwang

摘要:

青春期个体具有较高的药物成瘾易感性。通过啮齿类动物研究发现, 青春期个体之间的社会互动能够影响成瘾药物的奖赏效应, 如同伴接触、社会隔离、同笼生活的同伴是否经过成瘾药物处理等, 都会使动物对药物线索的偏爱和药物反应的易感性发生改变。社会互动的这种作用途径可能包括两个方面:一是通过其自身的奖赏性质影响成瘾易感性; 二是通过社会学习, 如情绪感染、感知觉信息的传递等, 改变药物成瘾易感性。社会互动影响成瘾药物奖赏效应的机制仍需进行更深入的研究。

关键词: 社会互动, 青春期, 啮齿类动物, 药物成瘾

Abstract:

Adolescents have a higher susceptibility to drug addiction. According to the previous studies in rodents, the rewarding effects of addictive drugs can be affected by social interaction that includes contacting with conspecifics, social isolation and living with cage-mates in different pharmacological states. Two mechanisms may be involved in the impact of social interaction, one being related to social rewarding properties, and the other concerned with social learning like the transmission of emotions and perceptional information. Therefore, further study is needed to clarify the mechanism of the interaction between social factors and addictive drugs.

Key words: social interaction, adolescence, rodents, drug addiction