ISSN 1671-3710
CN 11-4766/R
主办:中国科学院心理研究所
出版:科学出版社

心理科学进展 ›› 2020, Vol. 28 ›› Issue (10): 1713-1722.doi: 10.3724/SP.J.1042.2020.01713

• 研究前沿 • 上一篇    下一篇

睡眠时型与抑郁的关系及其机制 *

陈永进, 黄惠珍, 支愧云(), 张尚贤, 林秋韵, 王庆娅, 安蔚   

  1. 重庆大学公共管理学院, 重庆 400044
  • 收稿日期:2019-11-27 出版日期:2020-10-15 发布日期:2020-08-24
  • 通讯作者: 支愧云 E-mail:kyzhi@cqu.edu.cn
  • 基金资助:
    * 国家社会科学基金项目(18BGL209);中央高校基本科研业务费项目(2019CDJSK01PT04);重庆大学项目(2019GGXY03)

Relationship between chronotype and depression and its mechanism

CHEN Yongjin, HUANG Huizhen, ZHI Kuiyun(), ZHANG Shangxian, LIN Qiuyun, WANG Qingya, AN Wei   

  1. School of Public Affairs, Chongqing University, Chongqing 400044, China
  • Received:2019-11-27 Online:2020-10-15 Published:2020-08-24
  • Contact: ZHI Kuiyun E-mail:kyzhi@cqu.edu.cn

摘要:

抑郁症不仅严重影响个体的身心健康, 也加大了医疗保健的负担, 已成为全球关注的公共卫生问题。众多研究表明昼夜节律紊乱与抑郁症显著相关, 使睡眠时型成为探讨抑郁发生和发展的一个新视角。睡眠时型包括清晨型、中间型和夜晚型。夜晚型是抑郁的风险因素, 清晨型则是其保护性因素。情绪调节行为机制和杏仁核、扣带回皮质等神经机制的探讨, 可以帮助我们更好理解睡眠时型对抑郁的影响。未来研究还需要探索睡眠时型的多维结构, 增加前瞻性队列研究设计, 丰富心理和生理机制, 加强干预性的实证研究。

关键词: 抑郁, 睡眠时型, 情绪调节

Abstract:

As a worldwide public health challenge, depression negatively affects personal health and substantially increases the public burden of medical care. Prior research found a strong association between disrupted circadian rhythm and depression, suggesting the important role of chronotype in depression research. Individuals can be categorized into three general chronotypes: evening types (E-Types), morning types (M-Types), and neither type (N-Types). Most of studies show that evening types are independently associated with severe depressive symptoms, while morning types are a protective factor against depression. Behavioral mechanisms (such as emotion regulation) and neural mechanisms of amygdala and cingulate cortext may help us understand the effects of chronotype on depression. Future research should explore the sub-dimensions of chronotype, apply the prospective cohort design, and assess the proposed psychological and physiological mechanisms. In addition, the study has important implications to develop effective interventions to reduce depression.

Key words: depression, chronotype, emotion regulation

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