Social deficits in autism spectrum disorder: A perspective from the social motivation theory

doi:10.3724/SP.J.1042.2021.02209

Abstract

Abstract:

Social deficits are core symptoms of autism spectrum disorder (ASD). Previous studies, from a social cognition perspective, proposed that a deficit in theory of mind is the cause of social impairment. However, individuals with ASD already exhibited social motivation deficit traits prior to acquiring theory of mind. Furthermore, some individuals who were able to pass theory-of-mind tests continued to show decreased motivation when engaging in social interactions. Social motivation theory suggests that social motivation is an important internal force promoting human evolution and motivating and sustaining an individual's social activities. This theory also highlights that social impairments in ASD may be etiologically related to deficits in neural mechanisms of social motivation and provides a new interpretation of social deficits in terms of behavioral performance, neuroscience, and biology. It is important to further refine research on the neural mechanisms of social motivation, to clarify the scope of application of social motivation theory in individuals with ASD, and to investigate the value of social motivation theory in assessment diagnosis and clinical rehabilitation.

Key words: social motivation theory, autism spectrum disorder, social deficits, reward system

CLC Number:

R395

WANG Lei, HE Huizhong, BI Xiaobin, ZHOU Li, FAN Xiaozhuang. Social deficits in autism spectrum disorder: A perspective from the social motivation theory[J]. Advances in Psychological Science, 2021, 29(12): 2209-2223.

References 140

[1]	毕小彬, 范晓壮, 米文丽, 贺荟中. (2020). 高风险婴儿前瞻性纵向研究与孤独症谱系障碍早期识别. 心理科学进展, 28(3), 443-455.
[2]	古若雷, 徐鹏飞, 徐蕊, 施媛媛, 杨紫嫣, 王娱琦, 蔡华俭. (2016). 焦虑情绪对奖赏学习的影响. 心理科学进展, 24(4), 475-483.
[3]	郝艳斌, 王福兴, 谢和平, 安婧, 王玉鑫, 刘华山. (2018). 自闭症谱系障碍者的面孔加工特点--眼动研究的元分析. 心理科学进展, 26(1), 26-41.
[4]	贺荟中. (2013). 自然教学策略:自闭症干预的PRT技术. 华东师范大学学报(教育科学版), 31(4), 46-54.
[5]	黄丽佳, 袁勤俭. (2018). 印象管理理论及其在信息系统研究中的应用与展望. 现代情报, 38(11), 172-177.
[6]	静进. (2017). 孤独症谱系障碍神经心理机制. 中国实用儿科杂志, 32(4), 279-282.
[7]	雷卓凡, 王晋辉. (2015). 奖赏记忆改善焦虑行为的小鼠模型及机制初探. 生物化学与生物物理进展, 42(7), 662-673.
[8]	李开云, 陈功香, 傅小兰. (2018). 自闭症谱系障碍者的视运动知觉. 心理科学进展, 26(5), 831-845.
[9]	李琪, 许晶, 郑亚. (2017). 刺激前负波: 奖赏期待的电生理指标. 心理科学进展, 25(7), 1114-1121.
[10]	刘步云, 静进. (2014). 儿童的利他行为发展及相关神经机制. 中国心理卫生杂志, 28(6), 406-410.
[11]	刘春燕, 陈功香. (2019). 自闭症谱系障碍个体的焦虑:发生机制、评估与治疗. 心理科学进展, 27(10), 1713-1725.
[12]	刘春燕, 吕鑫源, 宋素涛, 陈功香. (2020). 关键反应训练对自闭症儿童的干预有效性--来自认知神经科学的证据. 中国特殊教育, (1), 38-44.
[13]	王磊, 陈杨漪, 贺荟中. (2020). 自闭症谱系障碍个体在视觉注意上的性别差异--基于人物面孔和限制性兴趣刺激的研究. 中国特殊教育, (5), 33-40.
[14]	汪寅, 臧寅垠, 陈巍. (2011). 从“变色龙效应”到“镜像神经元”再到“模仿过多症”--作为社会交流产物的人类无意识模仿. 心理科学进展, 19(6), 916-924.
[15]	魏寿洪, 曹坚, 米韬, 冯吉荣, 廖进. (2019). 孤独症谱系障碍儿童社会技能发展水平及其影响因素. 中国当代儿科杂志, 21(1), 77-81.
[16]	谢宇, 贺荟中, 范晓壮, 易立新. (2020). 自闭症儿童的生物运动知觉及偏转角度的影响研究. 全球教育展望, 49(4), 119-128.
[17]	郑杰, 陈燕惠. (2018). 注意缺陷多动障碍发病机制研究进展. 中国当代儿科杂志, 20(9), 775-780.
[18]	禚传君, 范勇. (2014). 孤独症谱系障碍的多模态神经影像学研究进展. 中华实用儿科临床杂志, 29(12), 883-888.
[19]	Abrams, D. A., Lynch, C. J., Cheng, K. M., Phillips, J., Supekar, K., Ryali, S., ... Menon, V.(2013). Underconnectivity between voice-selective cortex and reward circuitry in children with autism. Proceedings of the National Academy Sciences of the United States of America, 110(29), 12060-12065. doi: 10.1073/pnas.1302982110 URL
[20]	Althaus, M., Groen, Y., Wijers, A. A., Noltes, H., Tucha, O., & Hoekstra, P. J.(2015). Oxytocin enhances orienting to social information in a selective group of high-functioning male adults with autism spectrum disorder. Neuropsychologia, 79, 53-69. doi: 10.1016/j.neuropsychologia.2015.10.025 pmid: 26498227
[21]	American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (DSM-5®). Washington, DC: American Psychiatric Publishing.
[22]	Andreou, M., & Skrimpa, V.(2020). Theory of mind deficits and neurophysiological operations in autism spectrum disorders: A review. Brain Sciences, 10(6), 393. doi: 10.3390/brainsci10060393 URL
[23]	Annaz, D., Campbell, R., Coleman, M., Milne, E., & Swettenham, J.(2012). Young children with autism spectrum disorder do not preferentially attend to biological motion. Journal of Autism and Developmental Disorders, 42(3), 401-408. doi: 10.1007/s10803-011-1256-3 URL
[24]	Aoki, Y., Yahata, N., Watanabe, T., Takano, Y., Kawakubo, Y., Kuwabara, H., ... Yamasue, H.(2014). Oxytocin improves behavioural and neural deficits in inferring others' social emotions in autism. Brain, 137(11), 3073-3086. doi: 10.1093/brain/awu231 URL
[25]	Atkinson, A. P., Dittrich, W. H., Gemmell, A. J., & Young, A. W.(2004). Emotion perception from dynamic and static body expressions in point-light and full-light displays. Perception, 33(6), 717-746. pmid: 15330366
[26]	Auyeung, B., Lombardo, M. V., Heinrichs, M., Chakrabarti, B., Sule, A., Deakin, J. B., ... Baron-Cohen, S.(2015). Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism. Translational Psychiatry, 5(2), Article e507.
[27]	Baranek, G. T., Watson, L. R., Boyd, B. A., Poe, M. D., David, F. J., & McGuire, L.(2013). Hyporesponsiveness to social and nonsocial sensory stimuli in children with autism, children with developmental delays, and typically developing children. Developmental Psychopathology, 25(2), 307-320. doi: 10.1017/S0954579412001071 URL
[28]	Baribeau, D. A., & Evdokia, A.(2015). Oxytocin and vasopressin: Linking pituitary neuropeptides and their receptors to social neurocircuits. Frontiers in Neuroscience, 9, 335.
[29]	Bedford, R., Gliga, T., Shephard, E., Elsabbagh, M., Pickles, A., Charman, T., ... Johnson, M. H.(2017). Neurocognitive and observational markers: Prediction of autism spectrum disorder from infancy to mid-childhood. Molecular Autism, 8(1), 49. doi: 10.1186/s13229-017-0167-3 URL
[30]	Benning, S. D., Kovac, M., Campbell, A., Miller, S., Hanna, E. K., Damiano, C. R., ... Dichter, G. S.(2016). Late positive potential ERP responses to social and nonsocial stimuli in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 46(9), 3068-3077. doi: 10.1007/s10803-016-2845-y URL
[31]	Bosl, W. J., Tager-Flusberg, H., & Nelson, C. A.(2018). EEG analytics for early detection of autism spectrum disorder: A data-driven approach. Scientific Reports, 8(1), 6828. doi: 10.1038/s41598-018-24318-x URL
[32]	Bottini, S.(2018). Social reward processing in individuals with autism spectrum disorder: A systematic review of the social motivation hypothesis. Research in Autism Spectrum Disorders, 45, 9-26. doi: 10.1016/j.rasd.2017.10.001 URL
[33]	Cage, E., Bird, G., & Pellicano, E.(2016). Reputation management in children on the autism spectrum. Journal of Autism and Developmental Disorders, 46(12), 3798-3811. doi: 10.1007/s10803-016-2923-1 URL
[34]	Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J.(2002). Emotion and motivation: The role of the amygdala, ventral striatum, and prefrontal cortex. Neuroscience and Biobehavioral Reviews, 26(3), 321-352. pmid: 12034134
[35]	Chevallier, C., Grezes, J., Molesworth, C., Berthoz, S., & Happe, F.(2012). Brief report: Selective social anhedonia in high functioning autism. Journal of Autism and Developmental Disorders, 42(7), 1504-1509.
[36]	Chevallier, C., Kohls, G., Troiani, V., Brodkin, E. S., & Schultz, R. T.(2012). The social motivation theory of autism. Trends in Cognitive Sciences, 16(4), 231-239. doi: 10.1016/j.tics.2012.02.007 pmid: 22425667
[37]	Chevallier, C., Molesworth, C., & Happe, F.(2012). Diminished social motivation negatively impacts reputation management: Autism spectrum disorders as a case in point. PLOS ONE, 7(1), Article e31107.
[38]	Chita-Tegmark, M.(2016). Social attention in ASD: A review and meta-analysis of eye-tracking studies. Research in Developmental Disabilities, 48, 79-93. doi: 10.1016/j.ridd.2015.10.011 pmid: 26547134
[39]	Choi, U. S., Kim, S. Y., Sim, H. J., Lee, S. Y., Park, S. Y., Jeong, J. S., ... Cheon, K. A.(2015). Abnormal brain activity in social reward learning in children with autism spectrum disorder: An fMRI study. Yonsei Medical Journal, 56(3), 705-711. doi: 10.3349/ymj.2015.56.3.705 URL
[40]	Clements, C. C., Zoltowski, A. R., Yankowitz, L. D., Yerys, B. E., Schultz, R. T., & Herrington, J. D.(2018). Evaluation of the social motivation hypothesis of autism: A systematic review and meta-analysis. JAMA Psychiatry, 75(8), 797-808. doi: 10.1001/jamapsychiatry.2018.1100 pmid: 29898209
[41]	Constantino, J. N., Kennon-McGill, S., Weichselbaum, C., Marrus, N., Haider, A., Glowinski, A. L., ... Jones, W.(2017). Infant viewing of social scenes is under genetic control and is atypical in autism. Nature, 547(7663), 340-344. doi: 10.1038/nature22999 URL
[42]	Crawford, H., Moss, J., Oliver, C., Elliot, N., Anderson, G. M., & McCleery, J. P.(2016). Visual preference for social stimuli in individuals with autism or neurodevelopmental disorders: An eye-tracking study. Molecular Autism, 7, 24. doi: 10.1186/s13229-016-0084-x pmid: 27054022
[43]	Curtin, S., & Vouloumanos, A.(2013). Speech preference is associated with autistic-like behavior in 18-months-olds at risk for autism spectrum disorder. Journal of Autism and Developmental Disorders, 43(9), 2114-2120. doi: 10.1007/s10803-013-1759-1 URL
[44]	Damiano, C. R., Cockrell, D. C., Dunlap, K., Hanna, E. K., Miller, S., Bizzell, J., ... Dichter, G. S.(2015). Neural mechanisms of negative reinforcement in children and adolescents with autism spectrum disorders. Journal of Neurodevelopmental Disorders, 7(1), 12. doi: 10.1186/s11689-015-9107-8 pmid: 25829969
[45]	Dawson, G.(2008). Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder. Development and Psychopathology, 20, 775-803. doi: 10.1017/S0954579408000370 URL
[46]	Dawson, G., Toth, K., Abbott, R., Osterling, J., Munson, J., Estes, A., ... Liaw, J.(2004). Early social attention impairments in autism: Social orienting, joint attention, and attention to distress. Developmental Psychology, 40(2), 271-283. doi: 10.1037/0012-1649.40.2.271 URL
[47]	Dawson, G., Webb, S. J., & McPartland, J.(2005). Understanding the nature of face processing impairment in autism: Insights from behavioral and electrophysiological studies. Developmental Neuropsychology, 27(3), 403-424. doi: 10.1207/s15326942dn2703_6 URL
[48]	Deckers, A., Roelofs, J., Muris, P., & Rinck, M.(2014). Desire for social interaction in children with autism spectrum disorders. Research in Autism Spectrum Disorders, 8(4), 449-453. doi: 10.1016/j.rasd.2013.12.019 URL
[49]	Delmonte, S., Balsters, J. H., McGrath, J., Fitzgerald, J., Brennan, S., Fagan, A. J., ... Gallagher, L.(2012). Social and monetary reward processing in autism spectrum disorders. Molecular Autism, 3(1), 7. doi: 10.1186/2040-2392-3-7 pmid: 23014171
[50]	Demurie, E., Roeyers, H., Baeyens, D., & Sonuga-Barke, E.(2011). Common alterations in sensitivity to type but not amount of reward in ADHD and autism spectrum disorders. Journal of Child Psychology and Psychiatry, 52(11), 1164-1173. doi: 10.1111/jcpp.2011.52.issue-11 URL
[51]	Dichter, G. S., Damiano, C. A., & Allen, J. A.(2012). Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: Animal models and clinical findings. Journal of Neurodevelopmental Disorders, 4(1), 19. doi: 10.1186/1866-1955-4-19 URL
[52]	Dichter, G. S., Richey, J. A., Rittenberg, A. M., Sabatino, A., & Bodfish, J. W.(2012). Reward circuitry function in autism during face anticipation and outcomes. Journal of Autism and Developmental Disorders, 42(2), 147-160. doi: 10.1007/s10803-011-1221-1 URL
[53]	Dillon, D. G., Holmes, A. J., Jahn, A. L., Bogdan, R., Wald, L. L., & Pizzagalli, D. A.(2008). Dissociation of neural regions associated with anticipatory versus consummatory phases of incentive processing. Psychophysiology, 45(1), 36-49.
[54]	Dubey, I., Ropar, D., & Hamilton, A. F. D.(2015). Measuring the value of social engagement in adults with and without autism. Molecular Autism, 6(1), 35. doi: 10.1186/s13229-015-0031-2 URL
[55]	Dubey, I., Ropar, D., & Hamilton, A. F. D.(2017). Brief report: A comparison of the preference for viewing social and non-social movies in typical and autistic adolescents. Journal of Autism and Developmental Disorders, 47(2), 514-519.
[56]	Dubey, I., Ropar, D., & Hamilton, A.(2018). Comparison of choose-a-movie and approach-avoidance paradigms to measure social motivation. Motivation and Emotion, 42(2), 190-199. doi: 10.1007/s11031-017-9647-1 pmid: 29563653
[57]	Elsabbagh, M., Mercure, E., Hudry, K., Chandler, S., Pasco, G., Charman, T., ... Team, B.(2012). Infant neural sensitivity to dynamic eye gaze is associated with later emerging autism. Current Biology, 22(4), 338-342. doi: 10.1016/j.cub.2011.12.056 pmid: 22285033
[58]	Emerson, R. W., Adams, C., Nishino, T., Hazlett, H. C., & Piven, J. J.(2017). Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age. Science Translational Medicine, 9(393), Article eaag2882.
[59]	End, A., & Gamer, M.(2019). Task instructions can accelerate the early preference for social features in naturalistic scenes. The Royal Society, 6(3), Article 180596.
[60]	Evers, K., Steyaert, J., Noens, I., & Wagemans, J.(2015). Reduced recognition of dynamic facial emotional expressions and emotion-specific response bias in children with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 45(6), 1774-1784. doi: 10.1007/s10803-014-2337-x pmid: 25563453
[61]	Ewing, L., Pellicano, E., & Rhodes, G.(2013). Using effort to measure reward value of faces in children with autism. PLOS ONE, 8(11), Article e79493.
[62]	Federici, A., Parma, V., Vicovaro, M., Radassao, L., Casartelli, L., & Ronconi, L.(2020). Anomalous perception of biological motion in autism: A conceptual review and meta-analysis. Scientific Reports, 10(1), 4576. doi: 10.1038/s41598-020-61252-3 URL
[63]	Frost-Karlsson, M., Galazka, M. A., Gillberg, C., Gillberg, C., Miniscalco, C., Billstedt, E., ... Johnels, J. A.(2019). Social scene perception in autism spectrum disorder: An eye-tracking and pupillometric study. Journal of Clinical and Experimental Neuropsychology, 41(10), 1024-1032. doi: 10.1080/13803395.2019.1646214 pmid: 31362564
[64]	Gilbertson, L. R., Lutfi, R. A., & Weismer, S. E.(2017). Auditory preference of children with autism spectrum disorders. Cognitive Processing, 18(2), 205-209. doi: 10.1007/s10339-016-0787-0 pmid: 28004222
[65]	Gordon, I., Jack, A., Pretzsch, C. M., Wyk, B. V., Leckman, J. F., Feldman, R., ... Pelphrey, K. A.(2016). Intranasal oxytocin enhances connectivity in the neural circuitry supporting social motivation and social perception in children with autism. Scientific Reports, 6, 35054. doi: 10.1038/srep35054 URL
[66]	Gotts, S. J., Simmons, W. K., Milbury, L. A., Wallace, G. L., Cox, R. W., & Martin, A.(2012). Fractionation of social brain circuits in autism spectrum disorders. Brain, 135(9), 2711-2725. doi: 10.1093/brain/aws160 URL
[67]	Greene, R. K., Spanos, M., Alderman, C., Walsh, E., Bizzell, J., Mosner, M. G., ... Dichter, G. S.(2018). The effects of intranasal oxytocin on reward circuitry responses in children with autism spectrum disorder. Journal of Neurodevelopmental Disorders, 10(1), 12. doi: 10.1186/s11689-018-9228-y pmid: 29587625
[68]	Greene, R. K., Walsh, E., Mosner, M. G., & Dichter, G. S.(2019). A potential mechanistic role for neuroinflammation in reward processing impairments in autism spectrum disorder. Biological Psychology, 142, 1-12. doi: 10.1016/j.biopsycho.2018.12.008 URL
[69]	Grimm, C., Balsters, J. H., & Zerbi, V.(2020). Shedding light on social reward circuitry: (Un)common blueprints in humans and rodents. Neuroscientist, 27(2), 159-183. doi: 10.1177/1073858420923552 URL
[70]	Guastella, A. J., & Hickie, I. B.(2016). Oxytocin treatment, circuitry, and autism: A critical review of the literature placing oxytocin into the autism context. Biological Psychiatry, 79(3), 234-242. doi: 10.1016/j.biopsych.2015.06.028 pmid: 26257243
[71]	Guillon, Q., Hadjikhani, N., Baduel, S., & Rogé, B.(2014). Visual social attention in autism spectrum disorder: Insights from eye tracking studies. Neuroscience and Biobehavioral Reviews, 42, 279-297. doi: 10.1016/j.neubiorev.2014.03.013 URL
[72]	Hayden, B. Y., Parikh, P. C., Deaner, R. O., & Platt, M. L.(2007). Economic principles motivating social attention in humans. Proceedings of the Royal Society B-Biological Sciences, 274(1619), 1751-1756. doi: 10.1098/rspb.2007.0368 URL
[73]	Hedger, N., Dubey, I., & Chakrabarti, B.(2020). Social orienting and social seeking behaviors in ASD. A meta analytic investigation. Neuroscience and Biobehavioral Reviews, 119, 376-395. doi: 10.1016/j.neubiorev.2020.10.003 URL
[74]	Hirschler-Guttenberg, Y., Golan, O., Ostfeld-Etzion, S., & Feldman, R.(2015). Mothering, fathering, and the regulation of negative and positive emotions in high- functioning preschoolers with autism spectrum disorder. Journal of Child Psychology and Psychiatry, 56(5), 530-539. doi: 10.1111/jcpp.12311 URL
[75]	Hommer, D. W., Knutson, B., Fong, G. W., Bennett, S., & Varnera, J. L.(2010). Amygdalar recruitment during anticipation of monetary rewards:An event-related fMRI study. Annals of the New York Academy of Sciences, 985(1), 476-478.
[76]	Hornberg, H., Perez-Garci, E., Schreiner, D., Hatstatt-Burkle, L., Magara, F., Baudouin, S., ... Scheiffele, P.(2020). Rescue of oxytocin response and social behaviour in a mouse model of autism. Nature, 584(7820), 252-276. doi: 10.1038/s41586-020-2563-7 URL
[77]	Hsiung, E. Y., Chien, S. H. L., Chu, Y. H., & Ho, M. W. R.(2019). Adults with autism are less proficient in identifying biological motion actions portrayed with point-light displays. Journal of Intellectual Disability Research, 63(9), 1111-1124. doi: 10.1111/jir.12623 pmid: 31020725
[78]	Hui, K., Katayama, Y., Nakayama, K. I., Nomura, J., & Sakurai, T.(2020). Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches. Neurosciene and Biobehavioral Reviews, 110, 77-91.
[79]	Jaswal, V. K., & Nameera, A.(2019). Being versus appearing socially uninterested: Challenging assumptions about social motivation in autism. Behavioral and Brain Sciences, 42, 1-73.
[80]	Jiao, Y., Chen, R., Ke, X. Y., Chu, K. K., Lu, Z. H., & Herskovits, E. H.(2010). Predictive models of autism spectrum disorder based on brain regional cortical thickness. Neuroimage, 50(2), 589-599. doi: 10.1016/j.neuroimage.2009.12.047 pmid: 20026220
[81]	Jones, C. R. G., Swettenham, J., Charman, T., Marsden, A. S., Tregay, J., Baird, G., ... Happé, F.(2011). No evidence for a fundamental visual motion processing deficit in adolescents with autism spectrum disorders. Autism Research, 4(5), 347-357. doi: 10.1002/aur.v4.5 URL
[82]	Jones, W., & Klin, A.(2013). Attention to eyes is present but in decline in 2-6-month-old infants later diagnosed with autism. Nature, 504(7480), 427-431.
[83]	Kampe, K. K. W., Frith, C. D., Dolan, R. J., & Frith, U.(2002). Reward value of attractiveness and gaze. Nature, 416(6881), 602-602.
[84]	Kanat, M., Spenthof, I., Riedel, A., van Elst, L. T., Heinrichs, M., & Domes, G.(2017). Restoring effects of oxytocin on the attentional preference for faces in autism. Translational Psychiatry, 7(4), Article e1097.
[85]	Keifer, C. M., Dichter, G. S., McPartland, J. C., & Lerner, M. D.(2019). Social motivation in autism: Gaps and directions for measurement of a putative core construct. Behavioral and Brain Sciences, 42, e95. doi: 10.1017/S0140525X18002418 URL
[86]	Kim, K., Rosenthal, M. Z., Gwaltney, M., Jarrold, W., Hatt, N., McIntyre, N., ... Mundy, P.(2015). A virtual joy-stick study of emotional responses and social motivation in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 45(12), 3891-3899. doi: 10.1007/s10803-014-2036-7 URL
[87]	Kishida, K. T., de Asis-Cruz, J., Treadwell-Deering, D., Liebenow, B., Beauchamp, M. S., & Montague, P. R.(2019). Diminished single-stimulus response in vmPFC to favorite people in children diagnosed with autism spectrum disorder. Biological Psychology, 145, 174-184. doi: 10.1016/j.biopsycho.2019.04.009 URL
[88]	Klin, A.(1991). Young autistic children's listening preferences in regard to speech: A possible characterization of the symptom of social withdrawal. Journal of Autism and Developmental Disorders, 21(1), 29-42. pmid: 1828067
[89]	Klin, A., Jones, W., Schultz, R., Volkmar, F., & Cohen, D.(2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry, 59(9), 809-816. pmid: 12215080
[90]	Klin, A., Lin, D. J., Gorrindo, P., Ramsay, G., & Jones, W.(2009). Two-year-olds with autism orient to non-social contingencies rather than biological motion. Nature, 459(7244), 257-261. doi: 10.1038/nature07868 URL
[91]	Knoll, L. J., Magis-Weinberg, L., Speekenbrink, M., & Blakemore, S. J.(2015). Social influence on risk perception during adolescence. Psychological Science, 26(5), 583-592. doi: 10.1177/0956797615569578 pmid: 25810453
[92]	Kohls, G., Antezana, L., Mosner, M. G., Schultz, R. T., & Yerys, B. E.(2018). Altered reward system reactivity for personalized circumscribed interests in autism. Molecular Autism, 9, 9. doi: 10.1186/s13229-018-0195-7 URL
[93]	Kohls, G., Chevallier, C., Troiani, V., & Schultz, R. T.(2012). Social ‘wanting' dysfunction in autism: Neurobiological underpinnings and treatment implications. Journal of Neurodevelopmental Disorders, 4(10), 1-20. doi: 10.1186/1866-1955-4-1 URL
[94]	Kohls, G., Peltzer, J., Schulte-Ruther, M., Kamp-Becker, I., Remschmidt, H., Herpertz-Dahlmann, B., ... Konrad, K.(2011). Atypical brain responses to reward cues in autism as revealed by event-related potentials. Journal of Autism and Developmental Disorders, 41(11), 1523-1533. doi: 10.1007/s10803-011-1177-1 URL
[95]	Kohls, G., Schulte-Ruther, M., Nehrkorn, B., Muller, K., Fink, G. R., Kamp-Becker, I., ... Konrad, K.(2013). Reward system dysfunction in autism spectrum disorders. Social Cognitive and Affective Neuroscience, 8(5), 565-572. doi: 10.1093/scan/nss033 URL
[96]	Kohls, G., Thonessen, H., Bartley, G. K., Grossheinrich, N., Fink, G. R., Herpertz-Dahlmann, B., & Konrad, K.(2014). Differentiating neural reward responsiveness in autism versus ADHD. Developmental Cognitive Neuroscience, 10, 104-116. doi: 10.1016/j.dcn.2014.08.003 URL
[97]	Kuhl, P. K., Coffey-Corina, S., Padden, D., & Dawson, G.(2005). Links between social and linguistic processing of speech in preschool children with autism: Behavioral and electrophysiological measures. Developmental Science, 8(1), F1-F12.
[98]	Kühn, S., & Gallinat, J.(2012). The neural correlates of subjective pleasantness. Neuroimage, 61(1), 289-294. doi: 10.1016/j.neuroimage.2012.02.065 URL
[99]	Lawrence, K. E., Hernandez, L. M., Eilbott, J., Jack, A., Aylward, E., Gaab, N., ... Consortium, G.(2020). Neural responsivity to social rewards in autistic female youth. Translational Psychiatry, 10(1), 178. doi: 10.1038/s41398-020-0824-8 URL
[100]	Livingston, L. A., Shah, P., & Happe, F.(2019). Compensation in autism is not consistent with social motivation theory. Behavioral and Brain Sciences, 42, 2.
[101]	Mahendiran, T., Brian, J., Dupuis, A., Muhe, N., Wong, P. Y., Iaboni, A., & Anagnostou, E.(2019). Meta-analysis of sex differences in social and communication function in children with autism spectrum disorder and attention- deficit/hyperactivity disorder. Frontiers in Psychiatry, 10, 804. doi: 10.3389/fpsyt.2019.00804 pmid: 31749718
[102]	Mallise, C. A., Lane, A. E., Woolard, A. J., Whalen, O. M., Murphy, V. E., Karayanidis, F., & Campbell, L. E.(2020). The temperament features associated with autism spectrum disorder in childhood: A systematic review. Research in Developmental Disabilities, 104, 103711. doi: 10.1016/j.ridd.2020.103711 URL pmid: 32599501
[103]	Martina, F., Armstrong, V. L., Marie, S., & Smith, I. M.(2019). Initiation of joint attention and related visual attention processes in infants with autism spectrum disorder: Literature review. Child Neuropsychology, 25(3), 287-317. doi: 10.1080/09297049.2018.1490706 URL
[104]	Modahl, C., Fein, D., Waterhouse, L., & Newton, N.(1992). Does oxytocin deficiency mediate social deficits in autism? Journal of Autism and Developmental Disorders, 22(3), 449-451. pmid: 1400106
[105]	Murphy, P., Brady, N., Fitzgerald, M., & Troje, N. F.(2009). No evidence for impaired perception of biological motion in adults with autistic spectrum disorders. Neuropsychologia, 47(14), 3225-3235. doi: 10.1016/j.neuropsychologia.2009.07.026 URL
[106]	Neuhaus, E., Beauchaine, T. P., & Bernier, R.(2010). Neurobiological correlates of social functioning in autism. Clinical Psychology Review, 30(6), 733-748. doi: 10.1016/j.cpr.2010.05.007 pmid: 20570622
[107]	Nieuwenhuis, S., Aston-Jones, G., & Cohen, J.(2005). Decision making, the P3, and the locus coeruleus- norepinephrine system. Psychological Bulletin, 131(4), 510-532. pmid: 16060800
[108]	Over, H.(2016). The origins of belonging: Social motivation in infants and young children. Philosophical Transactions of the Royal Society B-Biological Sciences, 371(1686), 8.
[109]	Pankert, A., Pankert, K., Herpertz-Dahlmann, B., Konrad, K., & Kohls, G.(2014). Responsivity to familiar versus unfamiliar social reward in children with autism. Journal of Neural Transmission, 121(9), 1199-1210. doi: 10.1007/s00702-014-1210-6 URL
[110]	Parish-Morris, J., Chevallier, C., Tonge, N., Letzen, J., Pandey, J., & Schultz, R. T.(2013). Visual attention to dynamic faces and objects is linked to face processing skills: A combined study of children with autism and controls. Frontiers in Psychology, 4, 185. doi: 10.3389/fpsyg.2013.00185 pmid: 23596436
[111]	Paul, R., Chawarska, K., Fowler, C., Cicchetti, D., & Volkmar, F.(2007). "Listen my children and you shall hear": Auditory preferences in toddlers with autism spectrum disorders. Journal of Speech Language and Hearing Research, 50(5), 1350-1364. doi: 10.1044/1092-4388(2007/094) URL
[112]	Pellissier, L. P., Gandia, J., Laboute, T., Becker, J. A. J., & Merrer, J. L.(2018). μ opioid receptor, social behaviour and autism spectrum disorder: Reward matters. British Journal of Pharmacology, 175(14), 2750-2769. doi: 10.1111/bph.13808 pmid: 28369738
[113]	Richey, J. A., Rittenberg, A., Hughes, L., Damiano, C. R., Sabatino, A., Miller, S., ... Dichter, G. S.(2014). Common and distinct neural features of social and non-social reward processing in autism and social anxiety disorder. Social Cognitive and Affective Neuroscience, 9(3), 367-377. doi: 10.1093/scan/nss146 pmid: 23223206
[114]	Ruta, L., Fama, F. I., Bernava, G. M., Leonardi, E., Tartarisco, G., Falzone, A., ... Chakrabarti, B.(2017). Reduced preference for social rewards in a novel tablet based task in young children with autism spectrum disorders. Scientific Reports, 7(1), Article 3329.
[115]	Sasson, N. J., Dichter, G. S., & Bodfish, J. W.(2012). Affective responses by adults with autism are reduced to social images but elevated to images related to circumscribed interests. PLOS ONE, 7(8), Article e42457.
[116]	Sasson, N. J., & Touchstone, E. W.(2014). Visual attention to competing social and object images by preschool children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(3), 584-592. doi: 10.1007/s10803-013-1910-z pmid: 23918441
[117]	Scheeren, A. M., Banerjee, R., Koot, H. M., & Begeer, S.(2016). Self-presentation and the role of perspective taking and social motivation in autism spectrum disorder. Journal of Autism and Developmental Disorders, 46(2), 649-657. doi: 10.1007/s10803-015-2610-7 pmid: 26408326
[118]	Scheeren, A. M., Begeer, S., Banerjee, R., Terwogt, M. M., & Koot, H. M.(2010). Can you tell me something about yourself?: Self-presentation in children and adolescents with high functioning autism spectrum disorder in hypothetical and real life situations. Autism, 14(5), 457-473. doi: 10.1177/1362361310366568 pmid: 20841344
[119]	Scott-Van Zeeland, A. A., Dapretto, M., Ghahremani, D. G., Poldrack, R. A., & Bookheimer, S. Y.(2010). Reward processing in autism. Autism Research, 3(2), 53-67. doi: 10.1002/aur.122 pmid: 20437601
[120]	Shafritz, K. M., Bregman, J. D., Ikuta, T., & Szeszko, P. R.(2015). Neural systems mediating decision-making and response inhibition for social and nonsocial stimuli in autism. Progress in Neuropsychopharmacology and Biological Psychiatry, 60, 112-120. doi: 10.1016/j.pnpbp.2015.03.001 URL
[121]	Shic, F., Bradshaw, J., Klin, A., Scassellati, B., & Chawarska, K.(2011). Limited activity monitoring in toddlers with autism spectrum disorder. Brain Research, 1380(12), 246-254. doi: 10.1016/j.brainres.2010.11.074 URL
[122]	Shillingsburg, M. A., Bowen, C. N., & Shapiro, S. K.(2014). Increasing social approach and decreasing social avoidance in children with autism spectrum disorder during discrete trial training. Research in Autism Spectrum Disorders, 8(11), 1443-1453. doi: 10.1016/j.rasd.2014.07.013 URL
[123]	Silva, C., da Fonseca, D., Esteves, F.,& Deruelle, C.(2015). Motivational approach and avoidance in autism spectrum disorder: A comparison between real photographs and cartoons. Research in Autism Spectrum Disorders, 17, 13-24. doi: 10.1016/j.rasd.2015.05.004 URL
[124]	Sorcinelli, A., Ference, J., Curtin, S., & Vouloumanos, A.(2019). Preference for speech in infancy differentially predicts language skills and autism-like behaviors. Journal of Experimental Child Psychology, 178, 295-316. doi: S0022-0965(18)30228-5 pmid: 30448530
[125]	Sotoodeh, M. S., Taheri-Torbati, H., Hadjikhani, N., & Lassalle, A.(2021). Preserved action recognition in children with autism spectrum disorders: Evidence from an EEG and eye-tracking study. Psychophysiology, 58(3), 1-14.
[126]	Stavropoulos, K. K. M., & Carver, L. J.(2013). Research review: Social motivation and oxytocin in autism- implications for joint attention development and intervention. Journal of Child Psychology and Psychiatry, 54(6), 603-618. doi: 10.1111/jcpp.12061 URL
[127]	Stavropoulos, K. K. M., & Carver, L. J.(2014a). Effect of familiarity on reward anticipation in children with and without autism spectrum disorders. PLOS ONE, 9(9), Article e106667.
[128]	Stavropoulos, K. K. M., & Carver, L. J.(2014b). Reward anticipation and processing of social versus nonsocial stimuli in children with and without autism spectrum disorders. Journal of Child Psychology and Psychiatry, 55(12), 1398-1408. doi: 10.1111/jcpp.12270 URL
[129]	Todorova, G. K., Hatton, R. E. M., & Pollick, F. E.(2019). Biological motion perception in autism spectrum disorder: A meta-analysis. Molecular Autism, 10(1), 49. doi: 10.1186/s13229-019-0299-8 URL
[130]	Traynor, J. M., Gough, A., Duku, E., Shore, D. I., & Hall, G. B. C.(2019). Eye tracking effort expenditure and autonomic arousal to social and circumscribed interest stimuli in autism spectrum disorder. Journal of Autism Developmental Disorders, 49(5), 1988-2002. doi: 10.1007/s10803-018-03877-y URL
[131]	Uljarevic, M., & Hamilton, A.(2013). Recognition of emotions in autism: A formal meta-analysis. Journal of Autism and Developmental Disorders, 43(7), 1517-1526. doi: 10.1007/s10803-012-1695-5 pmid: 23114566
[132]	Wang, L. H., Chien, H. L., Hu, S. F., Chen, T. Y., & Chen, H. S.(2015). Children with autism spectrum disorders are less proficient in action identification and lacking a preference for upright point-light biological motion displays. Research in Autism Spectrum Disorders, 11, 63-76. doi: 10.1016/j.rasd.2014.12.004 URL
[133]	Wang, Y., Wang, M. J., Rong, Y., He, H. Z., & Yang, C. J.(2019). Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials. Research in Autism Spectrum Disorders, 64, 63-75. doi: 10.1016/j.rasd.2019.03.007
[134]	Williams, E. H., Cristino, F., & Cross, E. S.(2019). Human body motion captures visual attention and elicits pupillary dilation. Cognition, 193, 104029. doi: S0010-0277(19)30202-1 pmid: 31352014
[135]	Williams, E. H., & Cross, E. S.(2018). Decreased reward value of biological motion among individuals with autistic traits. Cognition, 171, 1-9. doi: S0010-0277(17)30280-9 pmid: 29101779
[136]	Wright, K., Kelley, E., & Poulin-Dubois, D.(2014). Schematic and realistic biological motion identification in children with high-functioning autism spectrum disorder. Research in Autism Spectrum Disorders, 8(10), 1394-1404. doi: 10.1016/j.rasd.2014.07.005 URL
[137]	Wright, K., Kelley, E., & Poulin-Dubois, D.(2016). Biological motion and the animate-inanimate distinction in children with high-functioning Autism Spectrum Disorder. Research in Autism Spectrum Disorders, 25, 1-11. doi: 10.1016/j.rasd.2016.01.005 URL
[138]	Yassin, W., Nakatani, H., Zhu, Y. H., Kojima, M., Owada, K., Kuwabara, H., ... Koike, S.(2020). Machine-learning classification using neuroimaging data in schizophrenia, autism, ultra-high risk and first-episode psychosis. Translational Psychiatry, 10(1), 278. doi: 10.1038/s41398-020-00965-5 pmid: 32801298
[139]	Yerys, B. E., Ruiz, E., Strang, J., Sokoloff, J., & Vaidya, C. J.(2013). Modulation of attentional blink with emotional faces in typical development and in autism spectrum disorders. Journal of Child Psychology and Psychiatry, 54(6), 636-643. doi: 10.1111/jcpp.12013 URL
[140]	Yu, L. D., & Wang, S. P.(2021). Aberrant auditory system and its developmental implications for autism. Science China-Life Sciences, 64(6), 861-878. doi: 10.1007/s11427-020-1863-6 URL