Abstract:  Subjective cognitive impairment (SCI) is referred to as a cognitive impairment complaints with no pathological aspects of objective evidence. In recent years it has become a hot topic of concern in the field of dementia research since researchers have found that SCI patients are more likely to suffer from AD, thus it is likely to be an earlier stage of AD and MCI. There are however, great differences in the prediction effect of SCI. This paper systematically reviews recent researches status of subjective cognitive impairment, including the concepts and measurement of subjective cognitive impairment, brain changes and bio-markers, and the relationship between SCI and AD and prospects for the future research.

Key words: subjective cognitive impairment, Alzheimer's disease, prediction