Abstract: It is a hot research spot that investigating the neural mechanism of deception using functional magnetic resonance imaging and detectting lie based on its findings. Various experimental paradigms are adopted for revealing the cognitive and neural mechanism of feigned memory impairment, intentional error, and interpersonal deception. Furthermore, traditional GKT and CQT paradigms are used for detecting lies. Previous studies have emphasized the core roles of the prefrontal and parietal cortices implicating in cognitive control process in deception, however, lie detection based on the activities in these regions poses insufficient accuracy rates. Aside from highlighting executive control process, future research should focus on other cognitive components of deception and seek new indications of lie detection from memory traces and deception outcome, and reveal the neural basis of deception trait.

Key words: deception, lie detction, fMRI