Abstract:

Previous neuroimaging researches proposed that one of the most important etiologies of depression is the impairment of structure and function of the prefrontal cortex. As a non-invasive technique, tDCS can alleviate depressive symptoms and improve impaired cognitive functions steadily and effectively by regulating cortical excitability through targeting at the prefrontal cortex. To achieve more extensive clinical application in the future, future studies should do more advanced researches from six orientations, such as the effectiveness of tDCS, individual differences, early prevention and intervention.

Key words: depression, dorsolateral prefrontal cortex, transcranial direct current stimulation (tDCS), treatment