人脑自适应多尺度功能连接的性别差异

doi:10.3724/SP.J.1042.2018.0567

心理科学进展 ›› 2018, Vol. 26 ›› Issue (9): 1567-1575.doi: 10.3724/SP.J.1042.2018.0567

人脑自适应多尺度功能连接的性别差异

段凯凯¹, 董昊铭²^,³^,⁴^,⁵, 苗丽雯¹, 苏学权⁶^,⁷, 相洁¹^,**(), 左西年²^,³^,⁴^,⁵^,⁷^,*()

1太原理工大学, 计算机科学与技术学院, 太原 030024
2中国科学院行为科学重点实验室, 北京 100101
3中国科学院大学, 心理学系, 北京 100049
4中国科学院心理研究所磁共振成像研究中心, 北京 100101
5中国科学院心理研究所, 脑与心智毕生发展研究中心, 北京 100101
6广西师范学院, 体育学院, 南宁 530000
7广西师范学院, 脑与教育重点实验室, 南宁 530001

收稿日期:2018-01-22 出版日期:2018-09-15 发布日期:2018-07-30
通讯作者: 相洁,左西年 E-mail:xiangjie@tyut.edu.cn;zuoxn@psych.ac.cn
基金资助:
国家自然科学基金(61503272);国家自然科学基金(61305142);国家自然科学基金(61373101);山西省自然科学青年基金(2015021090);山西省自然科学青年基金(201601D202042);山西省重点研发计划项目(201603D111014);博士后基金(2016M601287);虚拟现实技术与系统国家重点实验室开放课题(BUAA-VR-15KF-16);山西省回国留学人员科研资助项目(2016-037)

Sex differences in adaptive multi-scale functional connectivity of the human brain

DUAN Kaikai¹, DONG HaoMing²^,³^,⁴^,⁵, MIAO Liwen¹, SU Xuequan⁶^,⁷, XIANG Jie¹^,**(), ZUO XiNian²^,³^,⁴^,⁵^,⁷^,*()

1 College of Computer Science and Technology, Taiyuan University of Technology, Taiyuan 030024, China
2 CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing 100101, China
3 Department of Psychology, University of Chinese Academy of Sciences, Beijing 100049, China
4 Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
5 Research Center for Lifespan Development of Mind and Brain, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
6 Institute of Physical Education, Guangxi Teachers Education University, Nanning 530000, China
7 Key Laboratory of Brain and Education, Guangxi Teachers Education University, Nanning 530001, China

Received:2018-01-22 Online:2018-09-15 Published:2018-07-30
Contact: Jie XIANG,XiNian ZUO E-mail:xiangjie@tyut.edu.cn;zuoxn@psych.ac.cn

摘要/Abstract

摘要：

已有脑成像研究展示了男女脑功能差异, 但功能磁共振信号的频率划分通常基于主观经验, 使脑功能性别差异的生物学解释遭遇瓶颈。本文提出人脑自适应多尺度功能连接算法, 刻画功能连接的时空多尺度特性, 揭示出0.06~0.10 Hz的性别差异：男性较强的连接主要与边缘网络和腹侧注意网络有关, 女性较强的连接主要与腹侧注意网络、视觉网络和额顶网络有关。

关键词: 性别差异, 功能连接, 脑网络, 功能磁共振成像, 低频特性

Abstract:

Recent advances on functional magnetic resonance imaging (fMRI) demonstrated sex differences in the brain function. However, no standard on fMRI signal’s frequency division limited further biologically plausible explanation of these observations. In this work, we proposed a fast-multi-dimensional ensemble empirical mode decomposition to extract their multi-scale features of fMRI signal. We found that: this method can perform adaptive frequency allocation for the resting-state fMRI signal, whereby the built multi-scale function network in the frequency brain of 0.06 ~ 0.10 Hz showed significant sex differences regarding its connectivity; males had strong functional connectivity primarily within the limbic network and ventral attention network whereas females presented their strong functional connectivity mainly related to the visual network, ventral attention network and frontoparietal control network. These findings present a new method for the analysis of functional MRI images and provided brain imaging evidence on sex differences in functional connectomics.

Key words: sex differences, functional connectivity, brain network, functional magnetic resonance imaging, low frequency characteristics

中图分类号:

B845

段凯凯, 董昊铭, 苗丽雯, 苏学权, 相洁, 左西年. (2018). 人脑自适应多尺度功能连接的性别差异. 心理科学进展 , 26(9), 1567-1575.

Kaikai DUAN, HaoMing DONG, Liwen MIAO, Xuequan SU, Jie XIANG, XiNian ZUO. (2018). Sex differences in adaptive multi-scale functional connectivity of the human brain. Advances in Psychological Science, 26(9), 1567-1575.

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人脑自适应多尺度功能连接的性别差异

Sex differences in adaptive multi-scale functional connectivity of the human brain

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