ISSN 1671-3710
CN 11-4766/R
主办：中国科学院心理研究所
出版：科学出版社

心理科学进展 ›› 2016, Vol. 24 ›› Issue (5): 739-752.doi: 10.3724/SP.J.1042.2016.00739

• 研究前沿 • 上一篇    下一篇

自闭症谱系障碍的生物基础

武文佼1;张 鹏2   

  1. (1山西省朔州师范高等专科学校教育系, 山西朔州 036000) (2北京师范大学心理学院, 北京 100875)
  • 收稿日期:2015-09-18 出版日期:2016-05-15 发布日期:2016-05-15
  • 通讯作者: 张鹏, E-mail: zhangpsy@mail.bnu.edu.cn

Biological basis of autism spectrum disorders

WU Wen-Jiao1; ZHANG Peng2   

  1. (1 School of Education, Shuozhou Normal College, Shuozhou 036000, Shanxi, China) (2 School of Psychology, Beijing Normal University, Beijing 100875, China)
  • Received:2015-09-18 Online:2016-05-15 Published:2016-05-15
  • Contact: ZHANG Peng,E-mail: zhangpsy@mail.bnu.edu.cn

PDF (PC)

3345

被引次数

3

摘要：

自闭症谱系障碍是一组发病于生命早期, 由一系列生理、心理因素引起的神经发育障碍。遗传、脑神经结构、营养素等是自闭症谱系障碍的生物基础的重要来源。个体在孕育早期形成的大脑和机体异常可能是导致自闭症谱系障碍的关键。这种异常在出生后的发育中具体作用于神经活动、脑发育、免疫系统等生理途径。研究者们今后可以尝试横跨不同自闭症谱系障碍亚型、年龄和发育阶段, 开展横向与纵向相结合的大范围研究, 以进一步明确自闭症谱系障碍的生物基础。

关键词: 自闭症谱系障碍, 病理机制, 生物基础

Abstract:

Autism spectrum disorder is a set of neuro-developmental disorders caused by a series of physiological and psychological factors which occurs in early life. The current evidence of the biological basis of autism spectrum disorders is analyzed from genetics, brain structure, nutrients and other aspects. Brain and body abnormalities formed in individuals early gestation could be crucial to autism spectrum disorders. These abnormalities affect postnatal development, specifically on physiological pathway such as neural activity, brain development, immune system, inflammatory reactions et. al. In the future researchers could try to stretch across different subtypes of autism spectrum disorders, ages and developmental stages to carry out a large-scale study which combines horizontal and vertical views.

Key words: autism spectrum disorders, physiological pathway, biological basis