ISSN 1671-3710
CN 11-4766/R

心理科学进展 ›› 2019, Vol. 27 ›› Issue (5): 821-833.doi: 10.3724/SP.J.1042.2019.00821

• 研究前沿 • 上一篇    下一篇



  1. 温州医科大学体育科学学院, 浙江 温州 325035
  • 收稿日期:2018-06-07 出版日期:2019-05-15 发布日期:2019-03-20
  • 通讯作者: 崔荣荣
  • 基金资助:
    * 2014年浙江省教育厅一般项目资助(L201431802)

The regularity and mechanism on immune response of psychosocial stress

CUI Rongrong()   

  1. School of Physical Education & Health Care, East China Normal University, Shanghai 200241, China;Department of physical education, Wenzhou medical university, Wenzhou 325035, China
  • Received:2018-06-07 Online:2019-05-15 Published:2019-03-20
  • Contact: CUI Rongrong


心理社会应激会引起免疫系统发生免疫防御、免疫自稳和免疫监视方面的功能变化, 并随着应激刺激的时间和强度的变化而发生着异常与正常之间的动态转变。其机制与遗传、神经内分泌、自由基代谢和肠道菌群变化等生物学因素相关, 且小胶质细胞可能在其中起着重要的中介作用。诸多的生物学因素与年龄、性别和经济地位等人口学因素共同决定着心理社会应激的免疫反应发生发展。在其干预中, 运动疗法中的体育锻炼是极为值得重视的一种手段。

关键词: 心理社会应激, 免疫反应, 免疫系统


The psychosocial stress will make the immune system experience functional changes in aspects of immune defense, immune homeostasis and immune surveillance and also appear dynamic transition between abnormality and normality along with time and intensity of stress stimulation. Its mechanism is related to biological factors such as heredity, neuroendocrine, free radical metabolism and intestinal flora changes and the microglial cell maybe play an important mediating role in it. Lots of biological factors, demography factors such as age, gender and economic status as well as route jointly determine occurrence and development of immune reaction in psychosocial stress. As for its intervention, the physical exercise in kinesitherapy is a kind of method that is worthy of attention.

Key words: psychosocial stress, immune response, immune system