ISSN 1671-3710
CN 11-4766/R
主办:中国科学院心理研究所
出版:科学出版社

心理科学进展 ›› 2017, Vol. 25 ›› Issue (7): 1145-1161.doi: 10.3724/SP.J.1042.2017.01145

• 研究前沿 • 上一篇    下一篇

 产后抑郁的预测因素及神经生理机制

 靳宇倡1;  丁美月1,2   

  1.  (1四川师范大学教师教育与心理学院, 成都 610066) (2南阳理工学院, 河南 南阳 473000)
  • 收稿日期:2016-07-12 出版日期:2017-07-15 发布日期:2017-05-26
  • 通讯作者: 靳宇倡, E-mail: jinyuchang@gmail.com E-mail: E-mail: jinyuchang@gmail.com
  • 基金资助:
     国家自然科学基金(71673032)、国家社会科学基金项目(12XSH019)和国家社会科学基金项目(15BSH025)。

 Predictive factors and the neurophysiological mechanism of postpartum depression

 JIN Yuchang1; DING Meiyue1,2   

  1.  (1 School of Teacher Education, Sichuan Normal University, Chengdu 610066, China) (2 Nanyang Institute of Technology, Nanyang 473000, China)
  • Received:2016-07-12 Online:2017-07-15 Published:2017-05-26
  • Contact: JIN Yuchang, E-mail: jinyuchang@gmail.com E-mail: E-mail: jinyuchang@gmail.com
  • Supported by:
     

摘要:  产后抑郁是产后时期出现的抑郁症状, 对女性及其后代甚至家人都会造成严重的负面影响。产后抑郁稳定的预测因素是遗传基因、依恋风格、童年负性生活经历和激素水平的变化; 涉及的脑区和神经网络集中在前额叶皮层、扣带回、杏仁核和海马等脑区及相应神经网络。未来应在探索综合的预测模型、男性伴侣的对照试验和基于大脑可塑性特征的干预模式等方面展开深入研究。

关键词:  产后抑郁, 依恋风格, 童年不良经历, 激素水平, 神经机制

Abstract:  Postpartum depression (PPD) refers to the depression symptoms that appear in the postpartum period which has negative impact on the health and well-being of a large number of new mothers, their offspring, and the rest of their family’s members. In the present review, key predictive factors of PPD are discussed, including genetic gene, attachment styles, negative experience of the childhood and hormone level changes. The neural network and brain regions related to PPD are resided largely in the prefrontal cortex, the cingulate cortex, the amygdale, the hippocampus and the other parts in the brain and their corresponding neural network. Future research in this field should focus on exploring an integrated predictive model, an etiology model of PPD, controlled trials of male partners and an intervention model based on characteristics of brain plasticity.

Key words:  postpartum depression, attachment styles, adverse childhood experience, hormone level, neural mechanisms

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