ISSN 0439-755X
CN 11-1911/B
主办：中国心理学会
　　　中国科学院心理研究所
出版：科学出版社

心理学报 ›› 1989, Vol. 21 ›› Issue (4): 102-106.

• • 上一篇    下一篇

拥挤、抢食对自发性高血压大鼠发病的影响及作用机制的探讨

赵峰;王文;刘力生   

  1. 中国医学科学院心血管病研究所阜外医院,中国医学科学院心血管病研究所阜外医院,中国医学科学院心血管病研究所阜外医院 北京 ,北京 ,北京
  • 发布日期:1989-12-25 出版日期:1989-12-25
  • 通讯作者: 赵峰

EFFECT OF SHR COME ON AFTER STRESS AND MECHANISMS OF ACTION

Zhao Feng;Wang Wen;Liu Lisheng Cardiovascular Institute, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing   

  • Online:1989-12-25 Published:1989-12-25

摘要： 社会、心理压力与疾病的发生、发展及转归有着密切的联系。而社会、心理压力为什么会导致一些心身疾病的发生?为什么可使一些疾病加重?尚无满意答案。本文选用自发性高血压大鼠(SHR),在实验室应激的条件下,对比观察了动物的血压,并对其作用机制进行了初步探讨。发现:心理紧张状态可以导致有高血压遗传素质的SHR提前发病,而且可使病情不断加重;应激后SHR血浆神经递质(NE.E)和神经肽类物质(VIP)均明显增高。表明原发性高血压病的发生、发展与社会心理因素关系密切。

关键词: NULL

Abstract: Social-Psychological stress was closely related to psychosomatic dise-ases. Why could it cause psychosomatic diseases and worsen some di-seases? We have no satisfactory answers so far. The blood pressure of SHRbefor and after laboratory stress were compared in this experiment andpreliminary mechanisms of action studied. It was found that stressstate could cause SHR coming on beforehand and worsen the diseasescontinuously. After stress, the NE~*, E~* and VIP~* increased obviously,indicating that social-psychological stress was closely related to essentialhypertensiveness.

Key words: NULL