ISSN 0439-755X
CN 11-1911/B
主办:中国心理学会
   中国科学院心理研究所
出版:科学出版社

心理学报 ›› 1980, Vol. 12 ›› Issue (3): 81-87.

• • 上一篇    下一篇

群体隔离对大白鼠行为的影响及其与脑内单胺类神经介质含量的关系

汤慈美;林文娟   

  1. 中国科学院心理研究所 ,中国科学院心理研究所
  • 出版日期:1980-09-25 发布日期:1980-09-25
  • 通讯作者: 汤慈美

THE INFLUENCE OF SOCIAL ISOLATION ON BEHAVIOR IN RATS AND ITS RELATIONSHIP TO MONOAMINE NEUROTRANSMITTERS CONTENT IN THE BRAIN

Tang Ci-mei;Lin Wen-juan(Institute of Psychology, Academia Sinica)   

  • Online:1980-09-25 Published:1980-09-25

摘要: 观察表明,群体隔离(10—12周)的大白鼠,在开阔地方的自由活动和杀小鼠行为方面没受到明显影响,但隔离鼠在电击后格斗行为明显地增加了。隔离鼠脑内单胺类种经介质的含量无明显改变。在电击格斗后群居组和隔离组脑内DA含量均明显降低。群居组鼠端脑内NE含量增高,脑干内5-HIAA含量降低,但隔离组无上述改变。隔离鼠在注利血平、电击后格斗行为明显减少。对上述现象进行了讨论。

关键词: NULL

Abstract: Observations were made on the changes of behavior in rats such as free activity in the open field, muricide and shock-induced fighting behaviorafter social isolation for 10-12 weeks. Furthermore, the changes of monoa-mine neurotransmitters contents in the brain of the rat were determined and the effect of d-amphetamine and reserpine on shock-induced fighting beha-vior was observed. It was found that there was no obvious influence on freeactivity in the open field and muricide after social isolation. But the shock-induced fighting behavior increased significantly. No significant changes weredetected on monoamine neurotransmitters contents in the brain of sociallyisolated rats. After shock-induced fighting, the DA contents decreased bothin the brain of isolated rats and gregarious rats. NE contents increasedin the telencephalon of gregarious rats, and the 5-HIAA contents in thebrain stem decreased. But no such changes were detected in the brain ofisolated rats. Shock-induced fighting behavior lessened ter reserpine injection upon isolated rats. The probable explanations of the above-men- tioned phenomena are discussed.

Key words: NULL