ISSN 1671-3710
CN 11-4766/R
主办:中国科学院心理研究所
出版:科学出版社

心理科学进展 ›› 2016, Vol. 24 ›› Issue (8): 1228-1236.doi: 10.3724/SP.J.1042.2016.01228

• 研究前沿 • 上一篇    下一篇

疼痛恐惧的形成及其对疼痛知觉的影响

苏琳1,2;杨周1,2,3;Todd Jackson1,2;陈红1,2;黄承志3   

  1. (1西南大学认知与人格教育部重点实验室; 2西南大学心理学院, 重庆 400715) (3西南大学化学化工学院, 重庆 400715)
  • 收稿日期:2015-11-02 出版日期:2016-08-15 发布日期:2016-08-15
  • 通讯作者: 杨周, E-mail: yangz@swu.edu.cn
  • 基金资助:

    国家自然科学基金项目(31371037); 重庆市项目博士后资助(Xm2015102)。

The formulation of fear of pain and its influence on pain perception

SU Lin1,2; YANG Zhou1,2,3; JACKSON Todd1,2 ; CHEN Hong1,2; HUANG Cheng-zhi3   

  1. (1 Key Laboratory of Cognition and Personality, Southwest University, Chongqing 400715, China) (2 Faculty of psychology, Southwest University, Chongqing 400715, China) (3 School of Chemistry and Engineering, Southwest University, Chongqing 400715, China)
  • Received:2015-11-02 Online:2016-08-15 Published:2016-08-15
  • Contact: YANG Zhou, E-mail: yangz@swu.edu.cn

摘要:

脑岛、杏仁核是疼痛恐惧形成的重要神经网络中心。疼痛恐惧增强了慢性疼痛患者的疼痛知觉体验, 进而加剧抑郁、焦虑情绪和功能损伤程度。脑岛、杏仁核、前额皮层和前扣带回是疼痛恐惧影响疼痛知觉的重要神经基础。通过认知方法干预疼痛恐惧可以改善患者的抑郁、焦虑情绪, 减少功能损伤。未来研究应拓展疼痛恐惧的测量工具, 采用功能磁共振成像技术进一步揭示疼痛恐惧影响慢性疼痛患者疼痛知觉的神经机制。

关键词: 疼痛恐惧, 慢性疼痛, 疼痛知觉, 杏仁核, 脑岛

Abstract:

Insula and amygdala are crucial neural network center for the formulation of fear of pain (FOP). FOP exacerbates pain perceptual experiences in patients with chronic pain, and then enhances their depression, anxiety and functional disability. Insular, amygdala, prefrontal cortex, and anterior cingulate cortex are crucial neural substrates for the impact of FOP on pain perception. Reducing FOP by using cognitive intervention therapies can effectively decrease pain experience in patients with chronic pain, and improve their depression, anxiety problems, and daily function. Future studies should develop new measurement tools to assess FOP, and furthermore to reveal the neural mechanisms about the impact of FOP on pain perception in patients with chronic pain by using the functional magnetic resonance imaging technology.

Key words: fear of pain, chronic pain, pain perception, amygdala, insular