ISSN 1671-3710
CN 11-4766/R
主办：中国科学院心理研究所
出版：科学出版社

心理科学进展 ›› 2005, Vol. 13 ›› Issue (3): 341-347.

• • 上一篇    下一篇

线粒体与认知老化

卜翠萍,奚耕思   

  1. 陕西师范大学生命科学学院，西安710062
  • 收稿日期:2004-12-25 修回日期:1900-01-01 出版日期:2005-05-15 发布日期:2005-05-15
  • 通讯作者: 奚耕思

Mitochondrion And Cognitive Aging

Bu Cuiping，Xi Gengsi   

  1. College of Sciences, Shaanxi Normal University, Xi’an 710062, Shaanxi, China
  • Received:2004-12-25 Revised:1900-01-01 Online:2005-05-15 Published:2005-05-15
  • Contact: Xi Gengsi

PDF (PC)

2107

被引次数

13

摘要： 目前，心理学、生物学、社会学等多个学科都在关注认知老化。文章从生物学的角度，论述了线粒体和认知老化的关系；介绍了线粒体在数量、分布及其能量供应，Ca2+浓度的维持，引发神经细胞凋亡，及线粒体基因等几个方面对认知老化产生的影响；描述了老化过程中线粒体功能失常引起的认知障碍；从而，为后人对认知老化产生机制的深入研究提供一定的理论依据。

关键词: 线粒体, 认知老化, Ca2+, 神经细胞凋亡, 线粒体基因

Abstract: At present, many subjects, such as psychology, biology, sociology, etc, focus their attention on cognitive aging. From the point of view of biology, this paper mainly discussed the relation between the mitochondrion and cognitive aging. The mitochondrion as an important cell organ acts on the cognitive aging in many aspects, such as quantity, distribution, energy supply, Ca2+ concentrations, nerve cell apoptosis, and mitochondrial gene. When mitochondrial functions are abnormal in the aging course, the cognitive function may be influenced by the negative effects. These investigations may offer useful evidences for understanding the cognitive aging mechanism deeply.

Key words: mitochondrion, cognitive aging, Ca2+, nerve cell apoptosis, mitochondrial gene

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