ISSN 1671-3710
CN 11-4766/R
主办：中国科学院心理研究所
出版：科学出版社

心理科学进展 ›› 2019, Vol. 27 ›› Issue (suppl.): 69-69.

• • 上一篇    下一篇

自组织模型结合光学成像在初级视觉皮层功能的验证

金安琦a, 俞洪波a   

  1. a复旦大学,生命科学学院,生物物理学系,视觉研究实验室,上海,200438
  • 出版日期:2019-08-26 发布日期:2022-03-21

Confirmation with Optical Imaging of Self-organization Model in the Functional Organization of Primary Visual Cortex

Anqi Jina, Hongbo Yua   

  1. aVision Research Laboratory, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai 200433, China
  • Online:2019-08-26 Published:2022-03-21

摘要： 目的：动物初级视觉皮层的神经元形成多种功能柱。自组织模型在某些特性方面显出与实验结果的高度一致性。本研究旨在通过实验结合模型,建立实验数据与理论模型的接口,探讨脑功能图形成机制。
方法：自组织模型。模型可模拟不同物种初级视觉皮层的多种功能图。内源信号光学成像。实验中采用的波长为540nm及627nm。
结果：通过调整模型参数及实验数据比例,不同物种（猫、猴、雪貂）初级视觉皮层功能图可代入模型并保持相对稳定。以540nm波长照射皮层获得的最优方位功能图带有血管伪迹,模型可修正伪迹,并在627nm波长成像数据中得到验证。单次成像功能图信噪比较低,代入模型后可增强信噪比,并得到实验数据验证。
结论：自组织模型在不同物种间具有可代入性;对血管伪迹和噪声具有可修复性和可应用性。

关键词: 自组织模型, 光学成像, 功能图, 血管伪迹, 信噪比

Abstract: PURPOSE: Neurons in primary visual cortex are organized into multiple functional maps. Self-organization model is highly consistent with the experiment results in some aspect. We applied experimental data with self-organization model and established the interface between experimental data and theoretical model for further study of mechanism in brain function map.
METHODS: Self-organization model(SOM). SOM can simulate multiple functional maps in primary visual cortex of different species. Optical Imaging. Wavelengths for illuminant were 540nm(green) and 627nm(red).
RESULTS: Function map in primary visual cortex of different species (cat, monkey, ferret) can be substituted into SOM and stayed stable by adjusting the model parameters and ratio of experimental map. The prefered orientation maps obtained at 540nm with heavy vascular artifacts can be corrected by the model, the results were consistent with maps in 627nm.The low signal-to-noise ratio in functional maps with less repetitions imaging function image can be enhanced by SOM and also confirmed by experiment.
CONCLUSIONS: The self-organizing model was substitutable and compatible among different species. SOM had the ability to modify vascular artifact and noise.

Key words: Self-organization model, Optical Imaging, Functional Map, Vascular Artifact, Signal to Noise Ratio