ISSN 0439-755X
CN 11-1911/B
主办：中国心理学会
　　　中国科学院心理研究所
出版：科学出版社

心理学报 ›› 1986, Vol. 18 ›› Issue (4): 64-69. cstr: 32110.14.1986.00064

• • 上一篇    下一篇

听觉诱发和电刺激中脑下丘诱发大鼠听因性发作的比较

许小冬;邵郊   

  1. 北京大学心理学系 ,北京大学心理学系
  • 发布日期:1986-12-25 出版日期:1986-12-25

COMPARISON OF AUDIOGENIC SEIZURES INDUCED BY ELECTRICAL STIMULATION OF INFERIOR COLLICULUS WITH THOSE BY ACOUSTIC PRIMING

Xu Xiaodong;Shao Jiao Beijing University   

  • Online:1986-12-25 Published:1986-12-25

摘要： 用100微安、持续1至3秒的电流刺激正常大鼠的中脑下丘,每24小时刺激一次,经过20次之后,动物的听因性发作率可达75％,它与听觉诱发组的动物经过连续10次的铃声诱发后所达到的发作率(80％)十分接近,与无诱发的对照组动物的发作率相比,有显著差异。此结果进一步肯定了中脑下丘在听因性发作中的重要作用。

关键词: NULL

Abstract: Electrical stimulation of inferior colliculus can bring aboutaudiogenic seizures in normal rats. This was proved in a group of 28wistar rats. Through implanted electrodes their inferior colliculi werestimulated with AC current of 50 Hz, 0.1mA. for 1-3 seconds induration once a day. After twenty times of stimulation, the animalswere subjected to auditory test by a bell of 115 dB. 75% of themshowed typical seizures to the sound. This percentage approximates thatof the acoustically primed group.

Key words: NULL