ISSN 0439-755X
CN 11-1911/B
主办:中国心理学会
   中国科学院心理研究所
出版:科学出版社

心理学报 ›› 1983, Vol. 15 ›› Issue (1): 120-123.

• • 上一篇    下一篇

加压素对记忆巩固过程作用的研究 Ⅱ.GABA在加压素易化记忆巩固过程中作用的探讨

萧信生;万瑞谦;杜坤大   

  1. 南京大学生物系生理教研室 ,南京大学生物系生理教研室 ,南京大学生物系生理教研室
  • 出版日期:1983-03-25 发布日期:1983-03-25
  • 通讯作者: 萧信生

THE EFFECT OF VASOPRESSIN ON PROCESSES OF MEMORY CONSOLIDATION ——Ⅱ.The Role of GABA in the Processes of Vasopressin Facilitation of Memory Consolidation

Xiao Xin-sheng,Wan Rui-qian,Du Kun-da (Division of Physiology,Department of Biology,Nanjing University)   

  • Published:1983-03-25 Online:1983-03-25

摘要: 本文探讨了脑内GABA能神经元在加压素易化记忆巩固过程中的作用。结果表明,第三天建立实验后立即腹腔注射印防己毒素(picrotoxin,0.5mg/kg),消除了加压素对条件反应消退过程的延缓作用,而注射氨氧乙酸(aminooxy-acetic acid,20mg/kg)获得相反结果。 实验结果提示,脑内GABA能神经元可能参与了加压素对记忆巩固过程的易化作用。

关键词: NULL

Abstract: The role of GABA in the processes of memory consolidation as facilitatedby arginine-8-vasopressin (AVP) is studied.The results show that thefacilitatory effect of AVP on consolidation of memory disappears whenpicrotoxin (0.5mg/kg) is injected i.p.immediately after the third acquisitionsession.An opposite result is obtained when AOAA (20mg/kg) is administeredinstead of picrotoxin. The observation suggests that GABA might be involved in the processesof memory consolidation which is facilitated by AVP.

Key words: NULL