ISSN 1671-3710
CN 11-4766/R
主办:中国科学院心理研究所
出版:科学出版社

Advances in Psychological Science ›› 2015, Vol. 23 ›› Issue (7): 1196-1204.doi: 10.3724/SP.J.1042.2015.01196

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Atypical Brain Functional Connectivity in Autism Spectrum Disorders

ZHANG Fen; WANG Suiping; YANG Juanhua; FENG Gangyi   

  1. (Center for Studies of Psychological Application / School of Psychology, South China Normal University, Guangzhou 510631, China)
  • Received:2014-10-20 Online:2015-07-15 Published:2015-07-15
  • Contact: WANG Suiping, E-mail: suiping@scnu.edu.cn

Abstract:

Autism spectrum disorders (ASD) is a common neurodevelopmental disorder. These patients suffer from social, language, and behavioral disturbances, which are associated with abnormal functional connectivity of the brain. Compared with typically developing participants, autistic people show an abnormal brain pattern of cortical under-connectivity and local over-connectivity. This abnormal brain function connection is influenced by many factors, such as atypical brain structures, scanning state, individual development, and analysis methods. In order to better understand the potential mechanisms under autism brain connectivity, future research should examine both the brain structures and functions, and consider participants’ age, task status and other factors.

Key words: Autism Spectrum Disorders, Functional connectivity, fMRI