Abstract:

Cognitive reserve is the ability to optimize performance by utilizing different brain networks. It significantly influences the physiological function, cognitive function and the behavior results. Researches on cognitive reserve mainly focus on its measurement, and the application reaserch of cognitive reserve in cognitive aging. Consensus has been obtained on its quantification and the relationship with cognitive aging. However, controversies exist on its standardization, its relationship with cognitive decline rate and with brain pathology. Future research should not only further refine the quantification of cognitive reserve, explore the pathological mechanism of cognitive reserve, but also pay attention to the intervention of cognitive reserve on aging.

Key words: cognitive reserve, quantification, cognitive aging, physiological mechanism