Abstract: Blindness could lead to enhanced acuity in the remaining senses. Brain imaging and TMS researches found that the brain cross-model reorganization underlies this kind of behavior compensation: visual cortex is not remains ‘silent’ after visual deprivation but rather is recruited by other modalities to process sensory information in a functionally relevant manner. Neutral circuits are shaped by altered sensory experience consistently activating tentative neural connections, which might mediate the cross-modal plasticity.

Key words: blind, cross-modal, visual cortex, plasticity