Abstract: Finding a latent structure for personality traits has been consistently one of the focuses in personality research, while finding empirical evidence of culture-general or culture-specific nature for a personality structure is at present one of the important topics in personality research. Therefore, it can be seen that there have disputation over the number of factors (or dimensions) for such a personality structure, and over the adaptability of a structure from one culture to people of another culture. The present paper summarizes various findings resulted from a series of studies on CPAI (Chinese Personality Assessment Inventory) over the past period of 20 years to put forward a Six Factor Model (SFM). Based on the responses to IR and O factor of SFM from the samples of Chinese and American, the paper therefore suggest that the number of factors and culture-specific nature in any of the existing personality structures be only meaningful in terms of methodology and epistemology adopted by its researchers. The only way to find a personality structure of culture-general or culture-specific is to let personality psychologists of many cultural backgrounds work together equally

Key words: Personality Structure, CPAI, NEO-PI, SFM, IR factor, O factor, etic/emic