心理科学进展 ›› 2021, Vol. 29 ›› Issue (10): 1724-1739.doi: 10.3724/SP.J.1042.2021.01724
收稿日期:
2021-03-30
出版日期:
2021-10-15
发布日期:
2021-08-23
通讯作者:
王力
E-mail:wangli1@psych.ac.cn
基金资助:
CHEN Chen, WANG Li(), CAO Chengqi, LI Gen
Received:
2021-03-30
Online:
2021-10-15
Published:
2021-08-23
Contact:
WANG Li
E-mail:wangli1@psych.ac.cn
摘要:
对于精神障碍这一概念的理解, 传统DSM-ICD分类诊断系统和研究领域标准RDoC均基于潜变量视角, 认为精神障碍的症状由其潜在共同原因所致。这2种观点都忽略了症状间的相互作用。不同于分类和维度视角, Borsboom在2008年对精神障碍的概念化提出了的全新视角——心理病理学网络理论。此理论的核心观点是症状之间的动态因果关系构成了精神障碍。基于心理病理学网络理论的网络分析方法, 主要以结合EBIC的glasso算法估计症状间的偏相关网络, 并通过网络中节点中心性与网络连接性等指标, 来考查精神障碍症状的不同特性。近几年来, 研究者发现心理病理学网络分析方法在对症状间因果关系的推断、核心症状的识别和网络结构的可靠性与可重复性方面仍面临一些挑战。这些挑战为心理病理学网络理论与方法指明了未来可能的发展方向。
中图分类号:
陈琛, 王力, 曹成琦, 李根. (2021). 心理病理学网络理论、方法与挑战. 心理科学进展 , 29(10), 1724-1739.
CHEN Chen, WANG Li, CAO Chengqi, LI Gen. (2021). Psychopathological network theory, methods and challenges. Advances in Psychological Science, 29(10), 1724-1739.
图1 分类诊断视角下, 创伤后应激障碍(PTSD)与其症状之间的关系(Borsboom & Cramer, 2013)。图顶部的椭圆形代表PTSD这一潜在疾病变量, 图底部的方框代表DSM系统中PTSD的症状:闯入性思维、噩梦、闪回等。此模型中, 箭头单向地从PTSD指向其可观测症状, 表示PTSD是引发这些症状的共同原因。
图2 RDoC倡议的精神障碍研究框架:研究应关注于负性效价系统、正性效价系统、认知系统、社会加工系统、唤起 / 调节系统和感觉运动系统这六大人类主要功能领域展开, 每个领域包含基因、分子、细胞、环路、生理、行为和自我报告这些基本分析单元。(资料来源:https://www.nimh.nih.gov/research/research-funded-by-nimh/rdoc/about-rdoc.shtml)
图3 心理病理学网络理论视角下的PTSD症状网络。17个节点分别代表DSM-IV中17个PTSD症状:闯入性思维、噩梦、闪回、情绪反应、生理反应、回避创伤相关想法、回避创伤提示活动、创伤相关遗忘、丧失兴趣、情感疏离、情感麻木、对未来的负性信念、睡眠问题、易激惹、注意力难以集中、高警觉、惊跳反应。节点间的绿边代表症状间的正相关, 红边代表负相关。边越粗, 相关性越高; 无边相连的节点间无相关。(资料来源:McNally et al., 2017)
图4 网络理论中精神障碍的发展阶段。阶段1为无症状阶段, 网络处于稳定的休眠状态; 阶段2为网络初步激活阶段, 某些症状被外部事件E1直接激活; 阶段3为症状传播阶段, 阶段2中被激活的症状激活与其相连接的症状; 阶段4为稳定的网络激活状态, 若网络连接紧密, 外部事件的消失不会使网络恢复, 即网络自我维持并持续处于激活状态。[资料来源:根据Borsboom (2017)绘制]
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