ISSN 1671-3710
CN 11-4766/R
主办：中国科学院心理研究所
出版：科学出版社

心理科学进展 ›› 2013, Vol. 21 ›› Issue (10): 1763-1769.doi: 10.3724/SP.J.1042.2013.01763

• 研究前沿 • 上一篇    下一篇

社交焦虑障碍的功能连接异常

耿海洋;李雪冰   

  1. (1中国科学院心理研究所心理健康重点实验室, 北京 100101) (2中国科学院大学, 北京 100049)
  • 收稿日期:2013-03-05 出版日期:2013-10-15 发布日期:2013-10-15
  • 通讯作者: 李雪冰
  • 基金资助:

    国家自然科学基金项目(30900441, 30930031), 中国科学院心理健康重点实验室经费资助。

Abnormal Functional Connectivity in Social Anxiety Disorder

GENG Haiyang;LI Xuebing   

  1. (1 Key laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China) (2 University of Chinese Academy of Sciences, Beijing 100049, China)
  • Received:2013-03-05 Online:2013-10-15 Published:2013-10-15
  • Contact: LI Xuebing

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摘要： In recent years, a growing number of studies have used resting-state functional MRI methods to explore the underlying brain mechanisms of social anxiety disorder (SAD), and reported abnormal functional connectivity between the amygdala and the prefrontal cortex as well as several resting-state networks, including the central executive network, the default model network, the self-referential network, the dorsal attention network and the core network, all of which play important role in the generation and maintenance of anxiety symptoms. The present study summarizes these findings of resting-state functional connectivity in SAD and provides evidence for a neural basis in the diagnosis and intervention of SAD in the future.

关键词: social anxiety disorder, resting-state network, functional connectivity, amygdala, prefrontal cortex

Abstract: 近年来, 越来越多的研究使用静息态功能磁共振成像方法研究社交焦虑障碍人群的静息态网络及其功能连接模式的异常, 发现社交焦虑障碍表现出以前额叶和杏仁核为核心的中央执行网络、默认网络、背侧注意网络等多个静息态网络以及杏仁核与前额叶之间的功能连接异常, 这可能成为社交焦虑障碍认知调控失败、自我信息加工偏向、注意偏差的重要神经表征。总结此类研究, 将有利于在连接和网络水平了解社交焦虑障碍的神经机制, 为社交焦虑障碍的诊断和治疗提供有力依据。

Key words: 社交焦虑障碍, 静息态网络, 功能连接, 杏仁核, 前额叶