Abstract: Social-Psychological stress was closely related to psychosomatic dise-ases. Why could it cause psychosomatic diseases and worsen some di-seases? We have no satisfactory answers so far. The blood pressure of SHRbefor and after laboratory stress were compared in this experiment andpreliminary mechanisms of action studied. It was found that stressstate could cause SHR coming on beforehand and worsen the diseasescontinuously. After stress, the NE~*, E~* and VIP~* increased obviously,indicating that social-psychological stress was closely related to essentialhypertensiveness.

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