ISSN 0439-755X
CN 11-1911/B

›› 1994, Vol. 26 ›› Issue (04): 417-422.

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QUANTITATIVE STUDIES FOR EFFECT OF TEMPORAL INFARCT ON LEARNING AND MEMORY IN WISTAR RATS

Xiang Jing;Kuang Peigen;Zhang Fengying(Neurotransmitter Research Laboratory,Chinese PLA General Hospital,Postgraduate Military Medical School,Beijing)   

  • Published:1994-12-25 Online:1994-12-25

Abstract: The selective temporal infarct animal model induced photochemically was developed,It was determined in terms of learning and memory ability,neurological functional score and size of infarct area coincidentally for quantitative study of the learning and memory disorders in Wistar rats with temporal infarct,The results demonstrated that the learning and memory ability of rats with temporal infarct was damaged significantiy,while no sensory and motor dysfunctions were found..It also showed that the extents of learning and memory ability damage were related to the size of the te mporal infarct area.It is suggested that the selected temporal infarct is an ideal animal model of dementia.

Key words: temporal infarct, learning, memory, area infarcted, neurological functional score