Abstract: Nine patients with ICVD and two control groups were examined with clinical memory scales. Their levels of CSF SP, VIP and SS were assayed after onset of ICVD. The results were as follows. 1. The total memory scores and MQ in ICVD were significantly lower than those of the two con- trol groups. In the subtest scores, the scores of associative learning and image recall also decreased. 2. The levels of CSF SS in patients with ICVD significantly decreased as compared with the controls. 3. The levels of CSF SS in patients with ICVD had a possitive correlation with MQ. The results suggested that there were memory disorders in patients with ICVD and the assay of CSF SS may be valuable to evaluate the memory conditions in patients with ICVD.

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