Abstract: The work of Kandel and his colleagues is reviewed. It shows theprogress made in the study of the neurobiological basis of learning andmemory in invertebrates. This article is divided into four parts:Behavioral observation, neural mechanism, studies at the molecular leveland comparison between sensitization and classical conditioning. Eachpart is subdivided into several sections. The author of this articleconsiders their work a breakthrough in the study of the neural cellmechanism of learning and memory.

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