Abstract: The effect of scopolamine on alimentary conditioning was investigated in 9 rabbits. Intraventricular injection Of scopolamine (30 or 45μg) caused a temporary depression of conditioned reflex, while the animals' food intake was not affected. The spontaneous unit activity of hippocampus was recorded in 22 awake ned restrained rabbits. After intraventricular injection of scopolamine (40μg) which inhibits the conditioning performance, the discharge rate of spontaneous unit activity showed no obvious changes; while after intraventricular injection of cholinergic agonist carbachol (6—8μg), the spontaneous unit activity showed some increase.

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