ISSN 0439-755X
CN 11-1911/B

›› 1982, Vol. 14 ›› Issue (02): 129-134.

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THE EFFECTS OF LASER GUIDED BY OPTIC FIBER INTO FRONTAL CORTEX AND NUCLEI CAUDATE ON THE TRANSMITTERS OF MONOAMI NES AND AMINOACIDS IN THE CORPUS STRIATUM OF RATS

Shen Zheng;Xiao Jian;Wang Li-hua;Lin Shu-zhi Department of Phychology, Beijing University   

  • Published:1982-06-25 Online:1982-06-25

Abstract: The article studied the changes in transmitters of monoamines andaminoacids in the brain corpus striatum of 52 rats under laser radiation guidedby optic fiber into the brain. The results are as follows: 1) He-Ne laser radiation (6328A, 0.04mw) lasting 3 minutes causessignificant decrease of 5-HT, 5-HIAA and increase of GABA. Besides, laserradiation to the cortex leads to significant increase of ASP and GA, laserradiation to nuclei caudate decreases DA and GA. 2) Nitrogen ultraviolet laser radiation (3371A 0.04mJ/pulse, 10 pulses/sec) causes significant increase of 5-HIAA, GABA, ASP and decrease of 5-HT. Besides, laser radiation to cortex decreases NE, but radiation to nucleicaudate causes decrease of DA. 3) Both He-Ne laser and nitrogen ultraviolet laser radiation to mixedstandard sample in vitro causes photolysis of ASP. Besides, nitrogen laser alsocauses the photolysis of NE and DA. The effects of laser radiation to thebrain on 7 kinds of transmitters in the corpus striatum does not mean a simplephoto-chemical process, but they are complicated effects on brain metabolismprocesses.

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