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Advances in Psychological Science    2019, Vol. 27 Issue (1) : 51-59     DOI: 10.3724/SP.J.1042.2019.00051
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Episodic memory performance and underlying brain mechanisms in elderly with subjective memory decline
YIN Shufei1(),LI Tian1,ZHU Xinyi2,3
1 Department of Psychology, Faculty of Education, Hubei University, Wuhan 430062, China
2 Center on Aging Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
3 Department of Psychology, University of Chinese Academy of Sciences, Beijing 100049, China
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Episodic memory (EM) is the collection of past personal experiences that have occurred at a particular time and place. Subjective decline in EM is reported in the elderly with subjective memory decline (SMD). The elderly with SMD have a faster rate of EM decline and a higher risk of developing Alzheimer's disease (AD) than do healthy controls. However, the brain mechanisms of episodic memory impairment in SMD are unclear. Previous studies suggest that even when memory performance has no observable deficits, the brain structure and function associated with EM have been abnormal in SMD. Two further studies are of vital scientific significance for understanding the pathogenesis of AD. One is to explore the abnormal key nodes and paths of memory neural circuits in SMD. The other is to reveal the changes in the neural circuits in the progression of AD. In addition, considering that the elderly with SMD are a special group with memory impairment, an in-depth investigation into the neural circuits in this group, will make a unique contribution to revealing the neural mechanism of human memory.

Keywords episodic memory      subjective memory decline      Alzheimer's disease      brain mechanisms      elderly     
ZTFLH:  B844  
Issue Date: 23 November 2018
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Shufei YIN
Tian LI
Xinyi ZHU
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Shufei YIN,Tian LI,Xinyi ZHU. Episodic memory performance and underlying brain mechanisms in elderly with subjective memory decline[J]. Advances in Psychological Science, 2019, 27(1): 51-59.
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