ISSN 0439-755X
CN 11-1911/B
主办：中国心理学会
　　　中国科学院心理研究所
出版：科学出版社

心理学报 ›› 1989, Vol. 21 ›› Issue (2): 81-84.

• • 上一篇    下一篇

心理性应激对人体血压、心率、呼吸及血浆、脑脊液中精氨酸加压素免疫活性物质含量的影响

杨俊;林葆城;王成海;宋朝佑;朱鹤年   

  1. 第二军医大学神经生物学教研室,第二军医大学神经生物学教研室,第二军医大学神经生物学教研室,第二军医大学神经生物学教研室,第二军医大学神经生物学教研室 上海 ,上海 ,上海 ,上海 ,上海
  • 发布日期:1989-06-25 出版日期:1989-06-25
  • 通讯作者: 杨俊

THE EFFECT OF PSYCHOLOGICAL STRESS ON HUMAN BLOOD PRESSURE, HEART RATE, RESPIRATORY FRE QUENCY AND THE CONTENTS OF IR-AVP IN PLASMA AND CEREBROSPINAL FLUID

Yang Jun;Lin Bao-cheng;Wang Cheng-hai;Song Chao-yao;Zhu He-nian Department of Neurobiology,The Second Military Medical College,Shanghai   

  • Online:1989-06-25 Published:1989-06-25

被引次数

48

摘要： 外伤性下肢畸形的12名患者,术前第三天和麻醉前,分别测量血压、心率和呼吸频率,同时用放射免疫分析法测定血浆、脑脊液中精氨酸加压素(AVP)的含量。实验结果表明,麻醉前收缩压、舒张压均显著升高,心率明显增快;AVP含量,血浆中降低,脑脊液中升高,两者呈负性相关(r_s=-0.656)。这提示心理性应激,可影响植物性神经系统活动,导致心血管功能的改变;加压素可能在心理性应激中发挥一定的作用。

关键词: NULL

Abstract: Twelve patients under psychological stress and nonstress condition were studied. Their blood pressure (BP), heart rate (HR) and respiratory frequency were determined, and their plasma and cerebrospinal fluid(CSF) ir-AVP were measured with radioimmunoassay(RIA). The results showed higher BP and faster HR in psychological stress than those in nonstress condition (p<0.01). There was no change in respiratory frequency. The plasma level of ir-AVP was much lower in those under psychological str- ess. A negative correlation between the plasma and CSF levels of ir-AVP was shown(r_s = - 0.656) in psychological stress condition. These findings suggest that psychological stress could have effect on the autonervous sy- stem to enhance the activation of circulatory system and AVP might play and important role.

Key words: NULL