Abstract: Zebrafish model has often been used in development, genetics and drug discovery studies. As a vertebrate model systems, the genetic makeup of the zebrafish shares high degree of homology with higher vertebrate including human. The central nervous system of zebrafish also has similarity to that of the mammalian animals. More recently, zebrafish has increasingly been used in studies of neuroscience and physiological psychology related areas. Researchers have investigated a wide range of behaviors in zebrafish larvae and adults. Taking advantage of the strength of the zebrafish model, genetic mutations and drug screening have been utilized to elucidate the molecular mechanism underlying the animal behaviors.

Key words: Zebrafish, behavioral model, behavioral development, genetic mutation, drug screen