Abstract:

The psychosocial stress will make the immune system experience functional changes in aspects of immune defense, immune homeostasis and immune surveillance and also appear dynamic transition between abnormality and normality along with time and intensity of stress stimulation. Its mechanism is related to biological factors such as heredity, neuroendocrine, free radical metabolism and intestinal flora changes and the microglial cell maybe play an important mediating role in it. Lots of biological factors, demography factors such as age, gender and economic status as well as route jointly determine occurrence and development of immune reaction in psychosocial stress. As for its intervention, the physical exercise in kinesitherapy is a kind of method that is worthy of attention.

Key words: psychosocial stress, immune response, immune system