ISSN 0439-755X
CN 11-1911/B

Acta Psychologica Sinica ›› 2020, Vol. 52 ›› Issue (7): 823-834.doi: 10.3724/SP.J.1041.2020.00823

• Reports of Empirical Studies • Previous Articles     Next Articles

Sound-induced flash illusion in older adults: Evidence from low-frequency fluctuation amplitudes in resting-state fMRI

ZHOU Heng1, HE Hua1, YU Wei2, WANG Aijun1(), ZHANG Ming1()   

  1. 1 Department of Psychology, Research Center for Psychology and Behavioral Sciences, Soochow University, Suzhou 215000, China
    2 Admission and Employment Office, Changchun University of Chinese Medicine, Changchun 130117, China
  • Received:2019-04-16 Published:2020-07-25 Online:2020-05-25
  • Contact: WANG Aijun,ZHANG Ming E-mail:ajwang@suda.edu.cn;psyzm@suda.edu.cn
  • Supported by:
    National Natural Science Foundation of China(31700939);National Natural Science Foundation of China(31871092);basic research program of Jiangsu Province(bk20170333);entrepreneurship and innovation training program of Suzhou University(201810285011z)

Abstract:

Auditory dominance means that the auditory information in multisensory integration is given priority and processed in a dominant position. Sound-induced flash illusion (SiFI) is a typical auditory dominance phenomenon, in which the visual perception of a stimulus for briefly heard voices, qualitatively changing at the same time, results in a fission illusion (F1B2) and a fusion illusion (F2B1). Previous studies have shown that older adults experience illusions more often than young adults. However, there is not yet a consensus regarding the mechanism when it is investigated using resting-state fMRI, though resting-state neural activity can reveal the intrinsic functional architecture of the brain (Fox & Raichle, 2007). Therefore, the present study aimed to investigate how amplitude of low-frequency ?uctuations (ALFF) was related to SiFI in older adults and would provide important novel insights into the differences in SiFI between older and young adults.

We selected 50 older adults (ages: 50~69 year old, M = 61.78, SD = 4.17) and 50 young adults (ages: 17~27 year old, M = 20.86, SD = 2.17). The present study was a 2 (participants: older vs. young adults) × 2 (flash number: 1 vs. 2) × 3 (sound number: 0 vs. 1 vs 2) mixed design. RS-fMRI data were collected by a magnetic resonance scanner in the participants’ natural state of wakefulness and relaxation. The RS-fMRI data were obtained by a Philips 3.0T magnetic resonance scanner, and the images of all participants’ resting states were obtained by gradient echoplanar imaging (EPI). The scan parameters were as follows: the TR = 2000 ms, TE = 30 ms, of view (FOV) = 220 mm × 220 mm, Turn corner = 90°, matrix = 64×64, Layer number = 36, layer thickness = 4 mm, with a thick layer of scanning time 400 s. We used the ALFF of the resting state of the brain to investigate the correlation between SiFI and spontaneous brain region activity in older and young adults to reveal SiFI differences. ALFF results were calculated using DPABI, a RS-fMRI data processing software (Yan et al., 2016).

From the perspective of the accuracy results, older and young adults both experienced fission and fusion illusions. However, regardless of experiencing a fission illusion or a fusion illusion, the size of illusion experienced by older adults was greater than that experienced by young adults. From the correlation analysis results of ALFF and illusions, there was a significant positive correlation between the F1B2 illusion and spontaneous medial prefrontal cortex (MPFC) activity in older adults, and there was a significant negative correlation between the F1B2 illusion and spontaneous activity in the right superior occipital gyrus (SOG) and the left lingual gyrus in young adults. For the F2B1 illusion, there was a significant negative correlation between the F2B1 illusion and spontaneous activity in the right superior occipital gyrus (SOG), the left lingual gyrus (IFG) and the right cerebellum, and a significant positive correlation between the F2B1 illusion and spontaneous activity in the left inferior frontal gyrus (IFG), the right middle frontal gyrus (MFG) and the left inferior temporal gyrus (ITG) in older adults. However, there was a significant positive correlation between the F2B1 illusion and spontaneous activity in the left superior frontal gyrus (SFG) in young adults.

The present study showed that the increased illusion experienced by older adults was related to spontaneous activity during resting states in multiple brain regions.

Key words: sound-induced flash illusion (SiFI), resting-state functional magnetic resonance imaging (RS-fMRI), amplitude of low-frequency ?uctuations (ALFF), fission illusion, fusion illusion