ISSN 0439-755X
CN 11-1911/B
主办:中国心理学会
   中国科学院心理研究所
出版:科学出版社

心理学报 ›› 2001, Vol. 33 ›› Issue (04): 80-84.

• • 上一篇    下一篇

应激对中国地鼠糖尿病发生的影响

吴大兴;姚树桥;邹涛;孙海霞;胡敏;刘幼硕   

  1. 中南大学湘雅二院医学心理研究中心 ,中南大学湘雅二院医学心理研究中心 ,中南大学湘雅二院医学心理研究中心 ,中南大学湘雅二院医学心理研究中心 ,中南大学湘雅二院代谢内分泌研究所,中南大学湘雅二院代谢内分泌研究所 长沙410011 ,长沙410011
  • 出版日期:2001-08-25 发布日期:2001-08-25
  • 通讯作者: 吴大兴

EFFECT BY EXPERIMENTAL STRESS ON THE ONSET OF DIABETES IN CHINESE HAMSTER

Wu Daxing ①\ Yao Shuqiao ①\ Zou Tao ①\ Sun Haixia ①\ Hu Min ②\ Liu Youshuo ② (① Chinical Psychological Research Center, ②Institute of Metabolism & Endocrinology, the Second Hospital of Xiangya, Zhongnan University, Changsha 410011)   

  • Online:2001-08-25 Published:2001-08-25

摘要: 研究实验性应激、情绪性、笼架水平在中国地鼠糖尿病发生中的作用强度及其交互作用 ,以确定中国地鼠糖尿病发生危险因素。结果表明实验性应激 (震动、旋转合并限制 )能促使中国地鼠血糖水平显著升高 ,糖尿病发病率增加 ,发病年龄提前 ;高情绪性中国地鼠 ,随着实验时间延长 ,其发病率也逐渐升高 ,并稳定在一定水平 ;析因方差分析提示 ,实验性应激与动物情绪性的交互作用对实验后中国地鼠的血糖变化起主要作用

关键词: 实验性应激, 情绪性, 笼架水平, 糖尿病, 中国地鼠

Abstract: The aim of this stndy was to investigate the role and interaction effects of experimental stress, emotionality and cage shelf level in spontaneous hereditary diabetes mellitus of Chinese Hamsters, and to find out risk factors in onset/incidence of animal diabetes. The results showed that incidence of diabetes mellitus and blood glucose level of Chinese Hamsters are significantly increased in the experimental stress (shaking, rotation and restraint); With experimental times lasting, high emotionality animals have a high incidence of disease and remained in steady level; A three way ANOVA suggested that interaction effects of experimental stress and animal emotionality play a main role in incidence of diabetes mellitus and blood glucose level of Chinese Hamster. In short, experimental stress and emotionality play an important role in the onset/incidence of diabetes mellitus of Chinese Hamster.

Key words: experimental stress, emotionality, cage shelf level, diabetes mellitus, Chinese Hamster