高风险婴儿前瞻性纵向研究与孤独症谱系障碍早期识别

毕小彬, 范晓壮, 米文丽, 贺荟中

Early identification of autism spectrum disorder in prospective longitudinal studies of high-risk infants

BI Xiaobin, FAN Xiaozhuang, MI Wenli, HE Huizhong

图1 高风险婴儿前瞻性纵向研究范式 注：(1)高风险婴儿(high-risk infants, HR infants)：ASD儿童的年幼同胞; (2)低风险婴儿(low-risk infants, LR infants)：正常发育儿童的年幼同胞; (3) ASD高风险婴儿(ASD high-risk infants, HR-ASD)：诊断为ASD的高风险婴儿; (4)非ASD高风险婴儿(non-ASD high-risk infants, HR-non-ASD)：未诊断为ASD的高风险婴儿; (5)正常发育高风险婴儿(high-risk infants with typical development, HR-Typical)：正常发育的高风险婴儿; (6)非正常发育高风险婴儿(high-risk infants with atypical development, HR-Atypical)：非正常发育但不符合ASD诊断标准的高风险婴儿。