Please wait a minute...
Advances in Psychological Science    2016, Vol. 24 Issue (Suppl.) : 76-     DOI:
|
Impaired motion salience and disconnection of ipsilateral FEF from the attention network in strabismic amblyopia
Hao Wang; Sheila Crewther; Minglong Liang; Robin Laycock; Tao Yu; Bonnie Alexander; David Crewther; Jian Wang; Zhengqin Yin
Southwest Eye Hospital/Southwest Hospital, Key Laboratory of Visual Damage and Regeneration and Restoration of Chongqing, Third Military Medical University, Chongqing 400038, China
School of Psychological Science, Faculty of Science, Technology and Engineering, La Trobe University, Melbourne, VIC 3086, Australia
Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China.
Centre for Human Psychophysiology, Swinburne University of Technology, VIC 3122, Australia.
Download: PDF(0 KB)  
Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks    
Abstract  

Purpose: To compare psychophysical performance and brain activation during a motion salience task and voluntary saccadesin adult strabismicamblyopes and controls.
Methods: The motion salience task involved discrimination and detection of a target of coherently moving dots. The second task required voluntary saccades to horizontal stimulus position changes. fMRI activation and functional connectivity between parieto-frontal attention network ROIs, and V1 and V5 were compared for the two tasks.
Results: Behavioural thresholds were higher for detection ofthe moving stimuli by the strabismic amblyopic eye compared to the fellow eye or control eyes. BOLD activation in IPS, FEF and V5 for both tasks, through the amblyopic eye was weaker than that to fellow eye or control subject eyes though no di?erence was seen in V1 activation to the motion task under any eye-viewing condition. Correlational connections between key nodes of the visual attention network activated by the amblyopic eye were abnormal in the motion task, with the FEF ipsilateral to the amblyopic eye the most isolated node.By contrast, the functional connections of this network were relatively normal for the voluntary saccade task.
Conclusions: Amblyopic eyes require slower speed and longer exposure for the detection of moving targets.Overall our results suggest that strabismic amblyopia is associated with reduced attention network activation during motion-driven attention tasks independent of V1.

Keywords Strabismic amblyopia;Visual attention      fMRI      Psychophysics     
Issue Date: 31 December 2016
Service
E-mail this article
E-mail Alert
RSS
Articles by authors
Cite this article:   
Hao Wang; Sheila Crewther; Minglong Liang; Robin Laycock; Tao Yu; Bonnie Alexander; David Crewther; Jian Wang; Zhengqin Yin. Impaired motion salience and disconnection of ipsilateral FEF from the attention network in strabismic amblyopia[J]. Advances in Psychological Science,2016, 24(Suppl.): 76-.
URL:  
http://journal.psych.ac.cn/xlkxjz/EN/     OR     http://journal.psych.ac.cn/xlkxjz/EN/Y2016/V24/ISuppl./76
[1] HAN Yan; SHE Ying; GAO Xiao. The cause of obesity: An explanation from food reward perspective[J]. Advances in Psychological Science, 2017, 25(3): 452-462.
[2] Rui Wang; Yuan Shen; Peter Tino; Andrew Welchman; Zoe Kourtzi. Cortico-striatal mechanisms for learning predictive statistics in the human brain[J]. Advances in Psychological Science, 2016, 24(Suppl.): 45-.
[3] Jinpeng Li; Zhaoxiang Zhang; Huiguang He. Visual Information Processing Mechanism Revealed by fMRI Data[J]. Advances in Psychological Science, 2016, 24(Suppl.): 57-.
[4] Nihong Chen; Bosco S. Tjan. Attention alters the orientation tuning for multiple-stimulus displays in human visual areas[J]. Advances in Psychological Science, 2016, 24(Suppl.): 73-.
[5] Peng Zhou; Jing Li; Jieqiong Wang; Likun Ai; Huiguang He. Abnormal Resting-State Interhemispheric Functional Connectivity in Ametropic Amblyopia[J]. Advances in Psychological Science, 2016, 24(Suppl.): 59-.
[6] Hao Zhou; Yijun Ge; Lan Wang; Peng Zhang; Sheng He. Feedback Signal Contributes to The Flash Grab Effect: Evidence from fMRI and ERP Study[J]. Advances in Psychological Science, 2016, 24(Suppl.): 33-.
[7] RAN Guang-Ming; CHEN Xu; ZHANG Xing; MA Yuan-Xiao. The neural mechanism for the superiority effect of social prediction[J]. Advances in Psychological Science, 2016, 24(5): 684-691.
[8] LEI Xu; ZHAO Wenrui. Simultaneous EEG-fMRI studies of sleep-dependent memory consolidation[J]. Advances in Psychological Science, 2016, 24(3): 327-334.
[9] SHI Yanwei; XU Fuming; WANG Wei; LI Yan; LIU Chenghao. Empathetic Social Pain: Evidence from Neuroimaging[J]. Advances in Psychological Science, 2015, 23(9): 1608-1616.
[10] LIANG Xiuling; LI Peng; CHEN Qingfei; LEI Yi; LI Hong. The Neural Correlates of Retrieval Practice in Learning and Memory Retention[J]. Advances in Psychological Science, 2015, 23(7): 1151-1159.
[11] ZHANG Fen; WANG Suiping; YANG Juanhua; FENG Gangyi. Atypical Brain Functional Connectivity in Autism Spectrum Disorders[J]. Advances in Psychological Science, 2015, 23(7): 1196-1204.
[12] ZHAO Qingbai; LI Songqing; CHEN Shi; ZHOU Zhijin; CHENG Liang. Dynamic Neural Processing Mode of Creative Problem Solving[J]. Advances in Psychological Science, 2015, 23(3): 375-384.
[13] CHENG Kai; CAO Guikang. Mind Wandering: Theoretical Hypotheses, Influential Factors and Neural Mechanisms[J]. Advances in Psychological Science, 2014, 22(9): 1435-1445.
[14] ZHANG XiaoLu;CHEN Xu. The Neural Mechanism of Adult Attachment Styles’ Differences in the Information Processing[J]. Advances in Psychological Science, 2014, 22(3): 448-457.
[15] ZHANG Yang-Yang;RAO Li-Lin;LIANG Zhu-Yuan;ZHOU Yuan;LI Shu. Process Test of Risky Decision Making: New Understanding, New Evidence Pitting Non-compensatory Against Compensatory Models[J]. Advances in Psychological Science, 2014, 22(2): 205-219.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
Copyright © Advances in Psychological Science
Support by Beijing Magtech