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Advances in Psychological Science    2015, Vol. 23 Issue (4) : 582-590     DOI: 10.3724/SP.J.1042.2015.00582
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Temporal Dynamic and Biological Mechanism of Memory Reconsolidation
ZENG Xiangxing; DU Juan; WANG Kaixin; ZHENG Xifu
(School of Psychology, South China Normal University, Guangzhou 510631, China)
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Memories are consolidated through the information encoding process during waking and the re- processing consolidation during sleeping. Memory reconsolidation theory claims that memory consolidation process needs to be repeated for many times. More specifically, it states that consolidated memories transiently return to a labile state upon each retrieval process and must be restabilized to persist further through a reconsolidation process involving new protein synthesis. At this labile state, memories are easily amenable to enhancement or disruption. Memory reconsolidation is also a time-dependent process, it occurs after memory consolidation and persists for about 6 hours, including the protein degradation destabilization phase and the protein synthesis stabilization phase. Re-exposure of the retrieval trial can trigger either memory reconsolidation or extinction, which depends on the duration of retrieval stimulus presentation.

Keywords memory consolidation      memory reconsolidation      temporal dynamic      biological mechanism     
Corresponding Authors: ZENG Xiangxing, E-mail:    
Issue Date: 15 April 2015
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ZENG Xiangxing
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ZENG Xiangxing,DU Juan,WANG Kaixin, et al. Temporal Dynamic and Biological Mechanism of Memory Reconsolidation[J]. Advances in Psychological Science, 2015, 23(4): 582-590.
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