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Advances in Psychological Science    2013, Vol. 21 Issue (6) : 990-998     DOI: 10.3724/SP.J.1042.2013.00990
Special Section of Physiological Psychology |
The Animal Model and Neurobiological Mechanisms of Maternal Separation
XUE Xiaofang;LI Man;WANG Weiwen;SHAO Feng
(1 Department of Psychology, Peking University, Beijing, 100871, China) (2 Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, China)
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Abstract  Establishment of animal models of schizophrenia through the social environmental deprivation was the focuses for understanding the neurobiological mechanisms underlying this severe mental disease. As an important means of early social environmental deprivation, maternal separation from birth to weaning is being regarding increasingly. By comprehensively describes the latest research results about the impact of maternal separation on rodent behavior and neurodevelopment, this article shows that the feasibility of maternal separation on studying schizophrenia; what's more, further analysis of the various factors which is influencing the results, provides some theoretical support for in-depth study in the future.
Keywords animal model      maternal separation      schizophrenia     
Corresponding Authors: SHAO Feng   
Issue Date: 15 June 2013
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XUE Xiaofang
LI Man
WANG Weiwen
SHAO Feng
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XUE Xiaofang,LI Man,WANG Weiwen, et al. The Animal Model and Neurobiological Mechanisms of Maternal Separation[J]. Advances in Psychological Science, 2013, 21(6): 990-998.
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http://journal.psych.ac.cn/xlkxjz/EN/10.3724/SP.J.1042.2013.00990     OR     http://journal.psych.ac.cn/xlkxjz/EN/Y2013/V21/I6/990
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